Presence of microglia in nervous tissue secondary to injury.
[microglia + G. -osis, condition]
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Astrocytosis confirmed by GFAP immunostaining (GRAESSER et al., 2006) and microgliosis confirmed by Iba-1 immunostaining (SOFRONIEW & VINTERS, 2010) were also present in our case.
At a biochemical and molecular level, ASH ameliorated the HFD-induced reactive gliosis and microgliosis and suppressed the expression of inflammatory markers such as RRARy, iNOS, MCP1, TNF[alpha], IL-1[beta] B and IL-6.
Youdim, "Iron involvement in neural damage and microgliosis in models of neurodegenerative diseases," Cellular and Molecular Biology, vol.
It showed that masitinib exerted neuroprotection by controlling microgliosis and neuroinflammation and ameliorating the aberrant glial cell proliferation in [SOD1.sup.G93A] rats [51].
Murugan et al., "Spinal microgliosis due to resident microglial proliferation is required for pain hypersensitivity after peripheral nerve injury," Cell Reports, vol.
In a recently published study on APPswe/PS1[DELTA]E9 mice, researchers were unable to demonstrate the presence of amyloid plaques, dystrophic neurites, neuronal loss, macro- or microgliosis, aberrant cell cycle re-entry, OS, tau hyperphosphorylation, or upregulation of proinflammatory cytokines or stress signaling molecules in the retina [56].
Connaughton et al., "Further characterisation of the LPS model of Parkinson's disease: a comparison of intra-nigral and intra-striatal lipopolysaccharide administration on motor function, microgliosis and nigrostriatal neurodegeneration in the rat," Brain, Behavior, and Immunity, vol.
Histologically, shared CNS lesions among the animals examined were moderate to marked lymphohistiocytic cell perivascular cuffing with marked vasculitis and neuronal degeneration, necrosis, and neurophagia with multifocal microgliosis and satellitosis (Figure 4).
The cytokine profiling array did not show diabetes-associated increases in classic proinflammatory cytokines such as IL-1[beta], TNF-[alpha], fractalkine, and IL-6 cytokines, which are associated with microgliosis and hyperalgesia [11, 20, 28, 29,31,32].
S100B gene ablation in mice protected them against 1-methyl -4-phenyl-1,2,3,6-tetrahydropyridine-(MPTP-) induced neurotoxicity via the reduction in microgliosis and expression of RAGE and TNF-[alpha] receptor [118].
Bolin, "Compromised reactive microgliosis in MPTP-lesioned IL-6 KO mice," Brain Research, vol.