microglia

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microglia

 [mi-krog´le-ah]
non-neural cells forming part of the adventitial structure of the central nervous system. They are migratory and act as phagocytes of waste products of the nervous system. adj., adj microg´lial.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

mi·crog·li·a

(mī-krog'lē-ă), This word is grammatically singular. Avoid the mispronunciation microgli'a.
Small neuroglial cells of the central nervous system, originating in the bone marrow, that may become phagocytic in areas of neural damage or inflammation.
[micro- + G. glia, glue]
Farlex Partner Medical Dictionary © Farlex 2012

microglia

(mī′krō-glē′ə, -glī′-)
n.
(used with a pl. verb) Any of the small neuroglial cells of the central nervous system having long processes and amoeboid and phagocytic activity at sites of neural damage or inflammation.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

microglial cell

A perivascular bone-marrow-derived cell native to the CNS, belonging to the mononuclear phagocytic system (e.g., monocytes, macrophages, dendritic cells and granulocytes), which presents antigens in an MHC-class-II restricted context.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

mi·crog·li·a

(mī-krog'lē-ă)
Small neuroglial cells, possibly of mesodermal origin, which may become phagocytic, in areas of neural damage or inflammation.
Synonym(s): Hortega cells.
[micro- + G. glia, glue]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Enlarge picture
MICROGLIA

microglia

(mi-krog'le-a) [? + glia, glue]
Cells of the central nervous system (CNS) present between neurons or next to capillaries. These cells may function as macrophages when they migrate to damaged CNS tissue.
See: gitter cell; illustration
Medical Dictionary, © 2009 Farlex and Partners

microglia

Neurological connective tissue MACROPHAGES. Compare MACROGLIA.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Hortega,

Pio del Rio, Spanish neurohistologist in South America, 1882-1945.
Hortega cells - small neuroglial cells that may become phagocytic in areas of neural damage or inflammation. Synonym(s): microglia
Hortega neuroglia stain - one of several silver carbonate methods to demonstrate astrocytes, oligodendroglia, and microglia.
Medical Eponyms © Farlex 2012
References in periodicals archive ?
The expressions of pro-inflammation genes of BV-2 microglia cells, including tumor necrosis factor-a (TNF)-a, IL-1[sz], and inducible nitric oxide synthase (iNOS), were detected by quantitative real-time PCR.
Since SPARC is a widely expressed profibrotic protein that modulates tissue physiology by altering cell-extracellular matrix interactions, it has the potential to mediate microglia cell proliferation and migration.
Inflammation and ischaemia--role of microglia cells
This year, Francis Lau, a molecular biologist in the Neuroscience Laboratory, published a study that investigated whether blueberry extracts could have a preventive effect on inflammatory signals coming from activated microglia cells.
Through a research grant, electroCore intends to provide up to one million dollars over a four-year period to Massachusetts General Hospital to conduct multiple preclinical studies, including initial work initiated in the second quarter of 2018 in the following areas: The effects of nVNS on persistent neuroinflammation and the neurological outcomes after concussive traumatic brain injury; and The effects of nVNS on microglia cells and their association with the development and progression of Alzheimer's disease.
They will also look at the collective impact on the microglia cells that protect the brain from injury, and experiment with the promising new drug.
Chemockine (C-C motif) ligand 2 (CCL2), a gene encoding for a factor recruiting inflammatory cells during the inflammatory response [32], was upregulated (2.1 [+ or -] 0.6-fold, n = 4) in microglia cells from LPS-treated animals (Figure 1(a)).
It is ascertained that A[beta] oligomers and fibrils stimulate microglia cells in a different manner [14,15].
Ghrelin blocks the TLR4/IKK/NF-[kappa]B pathway activation in microglia cells by indirect effects.
Expression of TNF-[alpha] and IL-1[beta] in microglia cells (arrows) is markedly enhanced following MCAO, but a noticeable reduction in TNF-[alpha] and IL-1[beta] expression can be observed in the activated microglia in the LXW7-treated rat brain.
The researchers found that during the first week of stress exposure, microglia cells undergo a phase of proliferation and activation, reflected by increased size and production of specific inflammatory molecules, after which some microglia begin to die.