microfold cells

microfold cells

specialized intestinal epithelial cells found in association with the lymphoid follicles, as in Peyer patches of the ileum; characterized by elaborate invaginations of their apical cell surface that harbor numerous lymphocytes and macrophages; believed to phagocytose antigens and present them to underlying lymphoid cells.
Synonym(s): M cell
References in periodicals archive ?
GP2 is found in microfold cells (M cells) of the follicular-associated epithelium in intestinal Peyer's patches (22).
The FAE microfold cells (M cells) sample luminal antigens and present them in Peyer's patches [38].
Generally, some bioactive polysaccharides were considered to modulate systemic immunity through microfold cells in the follicle-associated epithelium of the Peyer's patch (Volman et al.
(2012) The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells. Nat.
The physical/chemical barriers composed by IEL, Paneth cells (PC), microfold cells (M cells) or their products are impaired during the disease and fail to restrain bacterial invasion.
In addition to the pancreatic location of GP2, this glycoprotein was also detected on the microfold cells (M cells) of intestinal Peyer's patches (PP) representing the follicle-associated epithelium (FAE) in the intestine [23].