microfold cell

An intestinal mucosal cell that overlies Peyer’s patches and has microfolds instead of microvilli, which allows lymphocytes to approach the intestinal lumen without violating its integrity.

References in periodicals archive ?

Thus, upon reaching the large intestine, Shigella is taken up in vacuoles by microfold cell (M cells) which are specialized structure of the follicle associated epithelium which covers the mucosal lymphoid follicles, the stimulating site of the mucosal immune system (45 46).

Shigellosis: A Conformity Review of the Microbiology, Pathogenesis and Epidemiology with Consequence for Prevention and Management issues

In localised areas covering the lymphoid tissues, another type, the microfold cell (M Cell) is also present in small numbers.

Histogenesis of the muscularis mucosa in the human small intestine

GP2 is found in microfold cells (M cells) of the follicular-associated epithelium in intestinal Peyer's patches (22).

Differential diagnosis of Crohn's disease using antibodies to glycoprotein 2 and Saccharomyces cerevisiae

The FAE microfold cells (M cells) sample luminal antigens and present them in Peyer's patches [38].

Defensive Driving: Directing HIV-1 Vaccine-Induced Humoral Immunity to the Mucosa with Chemokine Adjuvants

Generally, some bioactive polysaccharides were considered to modulate systemic immunity through microfold cells in the follicle-associated epithelium of the Peyer's patch (Volman et al.

Type II arabinogalactan from Anoectochilus formosanus induced dendritic cell maturation through TLR2 and TLR4

(2012) The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells. Nat.

The mucosal immune system: from dentistry to vaccine development

The physical/chemical barriers composed by IEL, Paneth cells (PC), microfold cells (M cells) or their products are impaired during the disease and fail to restrain bacterial invasion.

Association among genetic predisposition, gut microbiota, and host immune response in the etiopathogenesis of inflammatory bowel disease

In addition to the pancreatic location of GP2, this glycoprotein was also detected on the microfold cells (M cells) of intestinal Peyer's patches (PP) representing the follicle-associated epithelium (FAE) in the intestine [23].

The novel Crohn's disease marker anti-GP2 antibody is associated with ileocolonic location of disease

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