They address its history, techniques, and ethical considerations; customized platform-based stereotactic deep brain stimulation lead placement technique; microelectrode recording
methods; intraoperative imaging-based lead implantation; lesioning methods for movement disorders; computational modeling and tractography for deep brain stimulation targeting; closed-loop simulation methods; applications to Parkinson's disease, essential tremor, dystonia, obsessive-compulsive disorder, epilepsy, major depression, Tourette syndrome, psychiatric indications, and pediatrics; intraoperative research during deep brain stimulation surgery; and establishing a deep brain stimulation practice.
Whether factors such as age, sex, hypertension, anatomic target, or use of microelectrodes affect the risk of cerebral vascular events during the DBS surgery remains controversial.,, In this study, the authors retrospectively investigated factors possibly affecting the risk of cerebral vascular events (ICH or venous infarction) during DBS surgery in 268 patients (518 DBS electrodes), including patient age, sex, anatomic target, use or nonuse of microelectrode recording
(MER), number of MERs performed, number of channels used in MER, and other parameters.
Israel, "Microelectrode recording
duration and spatial density constraints for automatic targeting of the subthalamic nucleus," Stereotactic and Functional Neurosurgery, vol.
(MER) was routinely performed for all targets (the number of inserted electrodes ranging 1 to 3).
To make the electrode impalement technique more efficient, obtain a greater amount of experimental data, and have more precise current threshold values, the microelectrode recording
the APs remains fixed somewhere in the biological preparation, and the other microelectrode is impaled into many other sites of the papillary muscle for the determination of their thresholds.
After identifying the STN by microelectrode recording
(MER), the DBS electrodes were implanted and connected to an implanted programmable generator.
The benefits and risks of using microelectrode recording
(MER) can be related to the number of electrode passes made to localize the STN.
analyzed different power spectrum density methods with the aim to select one that minimizes the calculation time to be used in real time during deep brain stimulation surgery, concluding that the optimum method to perform the real-time spectral estimation of the beta band from the microelectrode recording
signal is Welch with Hamming windows of 1.5 seconds and 50% overlap.
Bilateral STN-DBS was conducted and one time of microelectrode recording
in both sides.
Pre-operative MRI and microelectrode recording
during surgery are necessary for patients who undergo DBS to determine the positions of electrodes.[sup] However, it could be difficult to follow this protocol for each experimental animal.