microdialysis


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mi·cro·di·al·y·sis

(mī'krō-dī-al'i-sis),
A method of studying extracellular fluid composition and response to exogenous agents, using a tiny tubular probe with a dialysis membrane and fluid flow rates of 1-3 mcL/minute, inserted into tissues.

mi·cro·di·al·y·sis

(mī'krō-dī-al'i-sis)
A method of studying extracellular fluid composition and response to exogenous agents, utilizing a tiny tubular probe with a dialysis membrane and fluid flow rates of 1-3 mcL/min, inserted into tissues.

mi·cro·di·al·y·sis

(mī'krō-dī-al'i-sis)
Method of studying extracellular fluid composition and response to exogenous agents.
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References in periodicals archive ?
This was done to (1) evaluate the analytical method for dipeptide quantification and (2) test whether microdialysis is suitable for dipeptide sampling from soil.
In our study, we evaluated the effects of unilateral fornix DBS on glucose metabolism changes by intracerebral microdialysis, and we then tested the levels of extracellular glucose, lactate, and pyruvate in the hippocampus in both aged and adult mice.
Sustained dopamine release induced by secretoneurin in the striatum of the rat: a microdialysis study.
On the contrary, microdialysis probes have much larger steel shaft diameter up to .5 mm.
The aim of the present study was to develop and validate an LC-MS/MS method for the measurement of PHT concentrations in different body compartments such as blood and saliva, as well as samples from brain tissue microdialysis often used in neurology and neurosurgery, where antiepileptic therapy is often mandatory [11,12], and to compare its efficiency with a formerly developed GC-MS method [8].
In our previous microdialysis study, performed in a subgroup of the FM women from the multicenter study, muscle IL-6 had increased significantly directly after repetitive muscle contraction, in line with this [47, 55].
Charles River announced the acquisition of Brains On-Line, a neuroscience-focused provider of microdialysis and in vivo efficacy and pharmacokinetics testing, in August.
Brains On-Line has operations in San Francisco, the Netherlands, and Germany, and provides microdialysis for CNS research, as well as in vivo efficacy and pharmacokinetics testing to provide critical data required to advance potential CNS therapies through the development process.
Due to the diversity of physiological functions associated with these neurotransmitters, many researchers measure the levels of GABA and glutamate in microdialysis samples [10], brain homogenates from experimental animals [11], and human cerebrospinal fluid and serum [12].
Tissue ischemia microdialysis assessments following severe traumatic haemorrhagic shock: lactate/pyruvate ratio as a new resuscitation end point?
Over a three-hour period, CNS samples were obtained using a microdialysis cannula surgically implanted into the lateral ventricle.