microcytosis


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microcythemia

 [mi″kro-si-the´me-ah]
a condition in which the erythrocytes are smaller than normal; see also microcytic anemia. Called also microcytosis.

mi·cro·cy·the·mi·a

(mī'krō-sī-thē'mē-ă),
The presence of many microcytes in the circulating blood.
Synonym(s): microcytosis
[microcyte + G. haima, blood]

microcytosis

The presence in the circulation of red cells with a mean corpuscular volume (MCV) of < 65 fL and a diameter of ≤ 6 µm. Microcytosis is typical of iron-deficiency anaemia and thalassemia; red cells are often low in iron.

microcytosis

Hematology RBCs with an MCV of < 65 fL and a diameter of ≤ 6 µm; microcytosis is typical of iron-deficiency anemia and thalassemia; RBCs may be low in iron. See Iron-deficiency anemia, Thalassemia. Cf Macrocystosis.

mi·cro·cy·the·mi·a

(mī'krō-sī-thē'mē-ă)
The presence of many microcytes in the circulating blood.
Synonym(s): microcytosis, microcythaemia.
[microcyte + G. haima, blood]
References in periodicals archive ?
This condition is asymptomatic, and is characterized by increased Hb [A.sub.2], red cell microcytosis, and no significant hemolytic anemia.
Also, anaemia was classified based on only mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH); increased reticulocyte count due to compensatory response to anaemia and/or the preoperative haematinics administered to some patients can spuriously raise the MCV value masking microcytosis. Confirmatory tests such as ferritin or soluble transferrin receptor measurement for the diagnosis of iron deficiency are not routinely performed at the selected centres.
Hypochromia usually follows microcytosis. Occasionally, severe hypochromia is associated with macrocytic red cells, termed leptocytes.
The heterozygous and homozygous states for Hb E are benign conditions clinically, but individuals often have red cell microcytosis and/or hypochromia.
Red cell calcium leak in congenital hemolytic anemia with extreme microcytosis. Blood.
Comparison of red cell distribution width ad a red cell discriminant function incorporating volume dispersion for distinguishing iron deficiency from beta thalassemia trait in patients with microcytosis. Sao Paulo Medical Journal.
Laboratory investigations were all within normal range, except for mild microcytosis. Urine microscopy revealed 5-10 RBC/hpf.
A normal RDW value and microcytosis suggest thalassemia carier state rather than iron deficiency anemia.
Thus, our results showed that IDA in patients with RA is characterized by RBC microcytosis and hypochromia, a reduction in serum iron and ferritin levels, and an increase in serum transferrin and erythropoietin concentrations (Table 2).
Molecular genotyping of [alpha]-thalassemia helps to diagnose unexplained microcytosis and thus prevents unnecessary iron supplementation [18].
Two gene deletions (--/[alpha][alpha] or -[alpha]/-[alpha]) cause alpha thalassemia trait (minor) with microcytosis and usually no anemia.