microcystin


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microcystin

(mī-krō-sis'tin),
Those compounds produced by Microcystis aeruginosa: potent hepatotoxins and probable tumor promoters.

microcystin

Any toxic, cyclic, non-ribosomal peptide produced by cyanobacteria, which has anticholinesterase activity or causes severe liver injury through DNA damage by activating endonucleases and inhibiting inhibit protein phosphatases types 1 and 2A. Topical exposure to microcystins causes skin and eye irritation, rhinorrhoea, vertigo and fatigue; parenteral exposure may cause death after initial exposure, often due to intrahepatic haemorrhage and hypovolemic shock. An epidemic of microcystin-related death occurred at a haemodialysis centre in Brazil due to impure water.

microcystin

a group of toxic cyclic decapeptides, the hepatotoxins in some cyanobacteria. See also microcystis, anabaena, gloeotrichia, oscillatoria, nostoc rivulare.
References in periodicals archive ?
Algae toxins--The Toledo Blade reported that a Lake Erie algal bloom producing microcystin toxins is one of the largest in history.
We obtained anti-phycocyanin from Bioss (Woburn, MA), microtiter ELISA plates from Corning (Corning, NY), microcystin LR and anti-FceRI from EMD Millipore Corporation (Billerica, MA), Eagle's Minimum Essential Medium (EMEM) from ATCC (Manassas, VA), and phycocyanin, G418, and pNPP substrate from Sigma-Aldrich (St.
two summers ago noted that sea otters in the saltwater bay inexplicably began dying of a freshwater toxin, microcystin, the same one OSU scientists found riding Oregon rivers.
Here's a simple analogy: I live in the Toledo, Ohio, area where, in the summer of 2014, algae blooms contaminated Lake Erie with a toxin called microcystin that can cause liver failure.
Some of the algae observed in the VSP and the GBL could be cayanobacterial, which may present with microcystin, a known hepatotoxin (Anderson, 2007; Dash et al.
Toledo officials warned residents not to use city water early Saturday after tests at one treatment plant showed readings for microcystin above the standard for consumption, most likely because of the algae.
As many as 400,000 people were told not to drink, cook with, or boil the tap water after a toxin called microcystin was found in the Toledo water supply on Friday.
Exposure to high levels of microcystin can cause abdominal pain, vomiting and diarrhea, liver inflammation, pneumonia and other symptoms, some of which are life-threatening.
Iron-stimulated growth and microcystin production of Microcystis novacekii UAM 250.
Among specific topics are oxygenic photosynthesis, molecular chaperons and stress tolerance, sensing and molecular responses to low temperature, regulatory mechanisms in response to osmotic stress, environmental factors regulating nitrogen fixation in heterocystous and non-heterocystous cyanobacteria, the role of spontaneous mutation in adaptations to anthropogenic and natural stress, and benthic Microcystin and climate change.
3,4) A liver sample from one of the deceased penguins was also submitted for microcystin analysis by enzyme-linked immunosorbent assay (ELISA), results of which were negative (Table 1).