In our study, most of the MRI grades fall into Grade II, moderate sized microcysts > 3 mm.
Moreover, biopsy could not grade microcysts' size criteria specifically as MRI does, especially in Grade III scenario.
Axial T2 W Sequence showing grade II adenomyosis with microcysts > 3mm.
Axial T2 W Sequence showing grade III adenomyosis with microcysts > 4mm and diffuse increased myometrial interface.
Histologically, this appears as dilated or "sacculated" endometrial glands admixed with small endometrial microcysts
IVCM measurements of the mean intraepithelial microcyst area and the subepithelial connective tissue density and AS-OCT measurements of the total area of the hyporeflective cystic spaces and of the bleb wall reflectivity were calculated using ImageJ software (http://rsb.info.nih.
Microcysts at the superonasal conjunctiva detected by IVCM before surgery were scattered, with an optically clear structure, round or oval-shaped surrounded by a hyperreflective wall with no signs of clustering.
In the postoperative period, mean microcysts area and density increased significantly, whereas the subepithelial connective tissue density decreased significantly till the 6th month and then increased again till the end of the follow-up period.
Comparing the "success" and "failure" groups (Table 4), the area and density of epithelial microcysts were higher in success group but without reaching statistical significance (p > 0.05).
Additional features, if present (1) Hemosiderin deposition (2) Calcification (3) Microcyst formation (4) Mitotic activity (5) Pleomorphism (6) Presence of gemistocytes (7) Vascular proliferation (8) Necrosis d.
K: Other Pathologic Features.--Hemosiderin deposition, calcification, and microcyst formation are nonspecific findings that occur in both malignant and benign CNS neoplasms.
In the cited study, the subjects were divided into two groups, uniform and multiform, based on qualitative data, such as layer multiplicity, subconjunctival separation, and the presence/ absence of microcysts
. However, the high-intensity volume ratio at 0.5 months did not correlate with the IOP at 12 months posttrabeculectomy in our present study, indicating that an early quantitative measure of bleb wall intensity was not prognostic of future IOP control.