Histoplasma capsulation is acquired by inhaling dust particles which contain bird or bat droppings that contain small spores (microconidia
), the infectious form of the fungus.
terreus has ability to produce microconidia
borne directly on a short conidiophores which arise laterally from vegetative hyphae(Walsh et al., 2003).
The shapes of hyphae, their thickness, color, septation status, presence of chlamydospores, microconidia
and macroconidia, their shape, membrane thickness, their mutual relationship and their relationship with the conidiophore to which they were attached were examined at high magnification (10x40, Olympus BX41, Olympus, Tokyo, Japan).
Fungal conidia (Type of macroconidia, shape, size and arrangement of microconidia
Infection by inhalation of aerosolized H capsulatum microconidia
primarily affects the lungs of immuno-suppressed individuals, although a variety of clinical presentations exist.
Infective propagules (microconidia
) reach the lower airways, where they constitute a primary complex, and possible dissemination of the fungus via lymphatic vessels and hematogenous spread to other organs are likely to happen.
Microscope slides with the reproductive structures from minimum cultivation were observed and photographed in a light microscope (Olympus BX51, coupled with a camera Olympus DP70), showing shape and size of microconidia
; size and septation of macroconidia, presence of isolate or chain chlamidospores.
cepae can produce macroconidia and microconidia
, however, in the field chlamydospores are major form of the pathogen inoculum (Cramer, 2000).
Although macroconidia are highly infectious, the epidemiological role of microconidia
is uncertain (WEBER, 2014).