Papillary
microcarcinoma of the thyroid--prognostic significance of lymph node metastasis and multifocality.
Background: A large proportion of the patients with papillary thyroid
microcarcinoma are young women.
Papillary thyroid
microcarcinoma: proposal of treatment based on histological prognostic factors evaluation.
The 3 patients with Graves disease all had papillary
microcarcinoma found incidentally on postoperative histology.
It can be classified into four categories: (1) thyroid carcinoma or
microcarcinoma as an incidental finding after total thyroidectomy for benign mass, (2) radiological incidental finding of thyroid carcinoma with positive FNA result, (3) apparent thyroid metastasis with primary tumor unidentified prior to final histological specimen, and (4) symptomatic ectopic thyroid tissue with apparent metastasis [1].
LiVolsi, "
Microcarcinoma of the thyroid," Advances in Anatomic Pathology, vol.
Carcinoma arising in thyroglossal duct remnants with cervical lymph node metastasis and
microcarcinoma in the thyroid.
Hay, of 535 patients with thyroid papillary
microcarcinoma, median tumor size was 8 mm in diameter.
Delay in intervention for low-risk papillary
microcarcinoma does not affect prognosis.
14 cases (35%) were of classical PTC, 4 cases (10%) of papillary
microcarcinoma, 6 cases (15%) of FVPTC, 1 case (2.5 %) of diffuse sclerosing variant of PTC, 5 cases (12.5%) of FC-MI, one case (2.5%) of FC-WI and 9 cases (22.5%) of cellular nodule.
Additionally, we found that five cases of papillary thyroid
microcarcinoma (PTMC) (7.9%) presented dedifferentiation in the thyroid (2/5, 40.0%) and lymph node (3/5, 60.0%), of which 2 cases (40.0%) were observed to be fatal (Table 6).
Second, histologically, the lymph nodes in our case did not exhibit extensive fibrosis or lymphocytic infiltrate as shown in two cases of papillary thyroid
microcarcinoma that regressed to less than 1.5 mm with metastasis to lymph nodes [10].
