microbiome


Also found in: Dictionary, Wikipedia.

microbiome

(mī′krō-bī′ōm′)
n.
1. The complete genetic content of all the microorganisms that typically inhabit a particular environment, especially a site on or in the body, such as the skin or the gastrointestinal tract.
Mentioned in ?
References in periodicals archive ?
When infection ensues, the microbiome is disrupted, causing community collapse with loss of diversity and overgrowth of pathogenic species.
Past studies had already matched key DNA sequences to known bacterial species, enabling the team to define each baby's microbiome, and to watch the effect of each practice at intervals over the first two years of life.
Little attention was paid to the microbiome until testing methods, such as whole genome sequencing, made the National Institutes of Health's Human Microbiome Project (HMP) and related research possible.
Our microbiome includes germs that fight off other germs and so it's good to conduct war exercises from time to time, meaning exposure to, or even taking in, new germs.
The microbiome is the ecosystem of good and bad bacteria living in the body," says Finn, a professor of medicine at the University of Illinois at Chicago.
In melanoma patients, there were differential signals in the gut microbiome of responders versus nonresponders, and I think the clincher was when we transplanted fecal samples from responders to nonresponders in germ-free mice, essentially reconstituting the microbiome and showing that it equally affected the systemic immunity and antitumor immunity when we implanted tumors, as well as response to checkpoint blockade," lead author Jennifer A.
16] Both environmental and host factors can affect the skin microbiome such as climate, body location, age, and gender.
Cambridge, Massachusetts-based immune and infectious disease therapeutics developer Vedanta Biosciences, an affiliate of PureTech Health (LSE: PRTC), has initiated a Phase 1a/1b, first-in-human, clinical trial of VE303, the company's lead, orally-administered microbiome therapeutic product candidate for recurrent Clostridium difficile infection, the company said.
Our discovery, with more research, could eventually lead to a preventative approach involving modifying the gut microbiome in infants to reduce the risk," she explained.
Rao to strengthen our scientific team and advance our understanding of the human microbiome as it relates to disease.
They tested the microbiome in cancer patients in two studies published in the journal Science, and connected specific species and the overall diversity of the microbiome to the efficacy of immunotherapy drugs.
MBut what's less well-known is that a key reason for ensuring good nutrition early in life is to nurture children's microbiome - the trillions of bacteria that live on and in us, but mainly in the gastrointestinal tract.