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microarray analysisA computerised, robotic technology used to rapidly analyse mutated or missing genes. Microarray analysis provides a way of simultaneously studying the interaction of a large numbers of genes with each other and with regulatory networks that control batteries of genes.
A robot precisely applies droplets containing functional DNA to glass slides; fluorescent labels are then attached to the DNA from the cell being studied. The labelled probes are allowed to hybridise to cDNA strands on the slides, which are then placed into a scanning microscope that can measure the fluorescence of each dot, the brightness of which serves to quantify the amount of a specific DNA fragment.