microangiopathy


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microangiopathy

 [mi″kro-an″je-op´ah-the]
a disorder involving the small blood vessels. adj., adj microangiopath´ic.
thrombotic microangiopathy formation of thrombi in the arterioles and capillaries; proposed name for a syndrome that would include both thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.

cap·il·la·rop·a·thy

(kap'i-lă-rop'ă-thē),
Any disease of the capillaries, often applied to vascular changes in diabetes mellitus.
Synonym(s): microangiopathy
[capillary + G. pathos, disease]

microangiopathy

/mi·cro·an·gi·op·a·thy/ (-an″je-op´ah-the) angiopathy involving the small blood vessels.microangiopath´ic
thrombotic microangiopathy  thrombi in arterioles and capillaries, as in thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.

microangiopathy

[mī′krō·an′jē·op′əthē]
Etymology: Gk, mikros + angeion, vessel, pathos, disease
a disease of the small blood vessels. Examples are diabetic microangiopathy, in which the basement membrane of capillaries thickens, and thrombotic microangiopathy, in which thrombi form in the arterioles and capillaries.

microangiopathy

Any defect of very small blood vessels, usually capillaries, which is most common in diabetes, especially if poorly controlled. Despite thickening of the vascular basement membranes by a hyaline-like material, which corresponds to advanced glycosylation end products (AGEs), the vessels are leaky and allow transvascular passage of plasma proteins. AGEs or advanced diabetic microangiopathy-induced ischaemia directly impacts on the retina, the kidney and the peripheral nerves.

microangiopathy

Vascular disease Any defect of very small blood vessels, usually capillaries, which is most common in DM. See Diabetic microangiopathy.

cap·il·la·rop·a·thy

(kap'i-lă-rop'ă-thē)
Any disease of the capillaries, often applied to vascular changes in diabetes mellitus.
Synonym(s): microangiopathy.
[capillary + G. pathos, disease]

cap·il·la·rop·a·thy

(kap'i-lă-rop'ă-thē)
Any disease of the capillaries.
Synonym(s): microangiopathy.
[capillary + G. pathos, disease]

microangiopathy

(mī´krōan´jēop´əthē),
n a disease of the small blood vessels.

microangiopathy

a disorder involving the small blood vessels.

cerebrospinal microangiopathy
in pigs is manifested by depression, incoordination, aimless wandering, circling and wasting. The characteristic microangiopathy is not restricted to the nervous system. Thought to be a sequel to chronic edema disease.
dietetic microangiopathy
one of the less commonly occurring lesions that can be prevented by the dietary addition of selenium and vitamin E.
thrombotic microangiopathy
formation of thrombi in the arterioles and capillaries.
References in periodicals archive ?
Hypertension is known to accelerate progression of microangiopathy due to increased vascular leakage.
These ULvWF multimers due to their thrombotic potential cause excessive platelet aggregation, resulting in widespread platelet rich thrombi which in turn results in the development of thrombotic microangiopathy.
Renal thrombotic microangiopathy caused by anti-VEGF-antibody treatment for metastatic renal-cell carcinoma.
Soliris is also approved in the US and European Union as the first and only treatment for patients with atypical hemolytic uremic syndrome (aHUS), a debilitating, chronic, ultra-rare and life-threatening genetic disorder characterized by complement-mediated thrombotic microangiopathy, or TMA (blood clots in small vessels).
Brain MRI is an essential tool to differentiate neurological complications due to thrombotic microangiopathy and CNS complications of hypertension.
Proteinuria and thrombotic microangiopathy secondary to anti-VEGF antibody (bevacizumab) therapy.
Pulmonary carcinomatous arteriopathy, also referred to as pulmonary tumor thrombotic microangiopathy, carcinomatous endarteritis, or embolic carcinomatosis, (1,2) is a rare and distinct form of pulmonary spread of solid malignant tumors.
Thrombotic Microangiopathy and Kidney Function Improved with Soliris in Pediatric Patients with aHUS -
Although our patient belonged to risk group 2 with a predicated overall survival of 67% and Non relapse mortality of 20%, he succumbed to multiorgan failure and cyclosporine induced microangiopathy.
5) Other less frequently reported pathologic findings include diffuse parenchymatous degeneration with gliosis and axonal dystrophy, diffuse and focal subpial gray matter necrosis, mineralizing microangiopathy, dystrophic calcification, and axonopathy.