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n. Abbr. miRNA
Any of various short, single-stranded RNA molecules that regulate gene expression by binding to messenger RNA molecules, usually in untranslated regions.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
microRNAAny of a group of short (generally 21 to 24 nucleotides in length), non-coding RNA molecules which fold upon themselves (“hairpins”) and are usually cleaved from larger hairpin-containing RNA (itself often processed from some portion of mRNA).
MiRNA is conserved through evolution and plays a role in RNA interference, destroying mRNA made by specific genes, suppressing gene expression and controlling translation of target mRNAs, thereby regulating critical aspects of plant and animal development.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
microRNA(mī′krō-ăr′ĕn″ā″) [″ + ″],
Oligonucleotides that prevent a variety of messenger RNAs from being transcribed from DNA or translated into proteins. They typically consist of 21 to 25 linked nucleotides.
Medical Dictionary, © 2009 Farlex and Partners
microRNAVery short segments of RNA involved in RNA INTERFERENCE and recently shown to be important elements in the development of plant structure. Many genes that code for microRNA have been found in many species including H. sapiens . There is much current speculation into their role in human development.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005