Over the next several weeks, the normal
mice continued to decline.
Researchers soon linked the deaths to a previously unknown type of hantavirus, and found that it was spread by deer
mice -- of which the Four Corners region that spring had a bumper crop because of heavy winter snow and rainfall, the U.
All 39
mice used were kept in individual cages, monitored for signs of infection, and bled retroorbitally 2 weeks later to test for seroconversion by using plaque-reduction neutralization tests.
When such "star" transgenic
mice appear, they have as much financial as knowledge value.
AC mouse was created in the FVB/N
mice by pronuclear injection of a v-Ha-ras transgene linked to a fetal zeta-globin promoter and an SV40 polyadenation/splice sequence (Leder et al.
Genetically-altered
mice consistently outperformed normal
mice in six tests of learning and memory; their brain cells showed increased sensitivity to new stimuli.
Mice engineered to have excess p16 have little islet-cell proliferation, even during youth, the researchers found.
Mice were housed in temperature-, light-, and humidity-controlled animal quarters under specific-pathogen-free conditions.
Lungs from the experimentally inoculated
mice were analyzed by the multiplex assay.
Following six weeks of treatment with endostatin, PSA levels in the
mice dropped to zero, indicating the prostate tumors had shrunk to a microscopic dormant state.
I was very surprised that I could only find two research articles in PubMed on these cancer-resistant/spontaneous-regression
mice, including the original description of the
mice in 2003 and the recently published article.
