Since GA3 derived from mevalonic acid
similarly to a juvenile hormone (JH), Uckan et al.
Abrogation of insulinlike growth factor-I (IGF-I) and insulin action by mevalonic acid
depletion: synergy between protein prenylation and receptor glycosylation pathways.
Diagnosis is based on genetic testing and elevated mevalonic acid
levels in urine.
Lupeol and sitosterol are distributed in plant kingdom, which their biosynthesis is via the mevalonic acid
(5) During attacks, urinary excretion of mevalonic acid
increases, and measurements have diagnostic value.
They are mainly synthesized by polymalonate, shikimic acid and mevalonic acid
pathways (Boustie and Grube, 2005).
Some precursors such as sodium acetate, mevalonic acid
lactone, casein acid hydrolysate have been investigated to enhance yield of ART in plant and cell cultures of A.
Also known as hyperimmunoglobulinemia D syndrome, MKD (OMIM 260920) is an autosomal recessive disease caused by mutations in the MVK gene (Table 1), encoding for the enzyme mevalonate kinase, involved in the ATP-dependent phosphorylation of mevalonic acid
(2004), the deficiency of P in the vegetable tissue of a plant may reduce the phosphorylation of mevalonic acid
, which means the initial step for the synthesis of isopentenyl pyrophosphate, through the classical route of mevalonate synthesised from acetyl coenzyme A, the main precursor of monoterpenes, such as citral and limonene (Bruneton, 1991; Lange et al., 1998).
They are usually synthesized in the leaves, stored in extracellular spaces between the cuticle and the cell wall, and basically constituted by terpenes, synthesized by the mevalonic acid
Also identified was a strong signal suggesting interaction between host ?d T cells and genes in the GAS mevalonic acid
synthesis pathway responsible for production of isopentenyl-pyrophosphate, a short-chain phospholipid that stimulates these T-cells.