metoclopramide


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Related to metoclopramide: metoclopramide HCl

metoclopramide

 [met″o-klo-prah´mīd]
a dopamine receptor antagonist and prokinetic agent that stimulates gastric motility, used as the hydrochloride salt as an antiemetic, an aid in gastrointestinal radiology and intestinal intubaion, and in treatment of gastroparesis and gastroesophageal reflux; administered orally, intravenously, or intramuscularly.

metoclopramide

(mĕt′ə-klō′prə-mīd′)
n.
A dopamine antagonist, C14H22ClN3O2, that stimulates movement in the upper gastrointestinal tract, used in its hydrochloride form to treat nausea, gastroesophageal reflux, and diabetic gastroparesis.

metoclopramide

An ANTIEMETIC drug also useful in the control of severe heartburn (REFLUX OESOPHAGITIS) in HIATUS HERNIA. The drug is on the WHO official list. Brand names are Gastrobid Continus, Gastromax and Maxolon. The drug is also formulated with paracetamol as a MIGRAINE treatment under the brand name Paramax.
References in periodicals archive ?
Metoclopramide initially used to treat nausea in migraine attacks, however, it is now widely used as a single agent for pain relief in migraine attacks.4
Group Three received Dexamethasone (8 mg) one minute before administration of anaesthesia and Metoclopramide (20 mg) before termination of anaesthesia (C).
Our results showed that the independent predictive factors for a long hospital stay were a history of cirrhosis, a history of previous acute cholecystitis, cholangitis, or pancreatitis, being on long-term anticoagulation with warfarin, having standard-pressure pneumoperitoneum (14mmHg), having been given metoclopramide as an intraoperative antiemetic drug, using an abdominal drain, having an NRS pain score of more than 3, having an oral analgesia requirement of more than 2 doses, complications, and private ward admission.
Patients in both groups received intravenous metoclopramide 10 mg every 8 hours for 6 consecutive days.
Conclusion: Ranitidine enhances the contractile effect of the gut in vitro and potentiates the prokinetic effect of metoclopramide. So we conclude that ranitidine is a better choice for patients suffering from gastroesophageal reflux disease (GERD) along with gastroparesis as it enhances the prokinetic effect of metoclopramide.
Akathisia, panic, agoraphobia, and major depression following brief exposure to metoclopramide. Psychopharmacol Bull.
(4) A group received metoclopramide (D1 and D2 receptor antagonist) group (6 rats): 1 mg/kg body weight[15]
The Results: When on the medications, women's breast milk production increased by 96% for those on domperidone and 94% for those on metoclopramide. Mild side effects were reported in 23% of the women.
Adult patients presenting to the emergency department at Monte-fiore Medical Center in New York with acute migraine were randomized to receive one of the three doses of metoclopramide in an IV infusion over 20 minutes coadministered with 25 mg diphenhydramine to prevent the development of extrapyramidal side effects such as akathisia.
Houston, TX, May 06, 2010 --(PR.com)-- Recently, researchers have observed a disturbing trend in neonatal units across the country: doctors prescribing Reglan -- also known by its generic name, metoclopramide -- to treat premature infants.
Formulations of aspirin 900 mg together with 10 mg of the antiemetic metoclopramide are better than placebo at reducing symptoms of nausea and vomiting, according to the findings of a Cochrane Systematic Review using data from 13 studies with 4,222 participants.
But sachet formulations combining the anti-sickness drug metoclopramide worked best at this, although they were no more effective at pain relief.