blunts nitric oxide-induced lipid peroxidation and death of retinal photoreceptors: a comparison with other anti-glaucoma drugs," Investigative Ophthalmology & Visual Science, vol.
Four of the five beta-adrenergic blockers have no human eye data: betaxolol (Betoptic), carteolol (Ocupress), levobunolol (Betagan), and metipranolol
, but there are two case reports for timolol (Betimol, Istalol, Timoptic, Timoptic-XE) showing no fetal harm in one newborn and growth restriction in the other.
Beta Blockers acebutolol, alprenolol, atenolol, betaxolol, bisoprolol, bunolol, carteolol, carvedilol, celiprolol, esmolol, labetalol, levobunolol, metipranolol
, metoprolol, nadolol, oxprenolol, pindolol, propranolol, sotalol, timolol
The antiglaucoma beta blockers include betaxolol (Betoptic), carteolol (Ocupress), levobetaxolol (Betaxon), levobunolol (Betagan), metipranolol (Optipranolol) and timolol (Betimol, Timoptic, Istalol).
Severe breathing difficulties, including death from bronchial tube spasms, have been reported with carteolol, levobunolol, metipranolol and timolol.
(21) However, nonselective beta-blockers (timolol, carteolol, levobunolol, metipranolol
) are associated with a number of adverse effects including bronchospasm, (33) bradycardia, and hypotension.
Bronchial and cardiovascular effects of ocular topical beta-antagonists in asthmatic subjects: comparison of timolol, carteolol and metipranolol
. J Clin Pharmacol 1989;29:97-101.