methyldopa


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methyldopa

 [meth″il-do´pah]
a phenylalanine derivative administered orally or intravenously as an antihypertensive agent.

methyldopa

/meth·yl·do·pa/ (-do´pah) a phenylalanine derivative used in the treatment of hypertension.

methyldopa

(mĕth′əl-dō′pə)
n.
A drug, C10H13NO4, used to treat hypertension.

methyldopa

[-dō′pə]
an alpha2 receptor agonist that acts in the central nervous system to decrease sympathetic nervous system outflow.
indications It is prescribed for the reduction of hypertension in moderate to severe cases.
contraindications Use of monoamine oxidase inhibitors, liver dysfunction, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are liver toxicity and blood dyscrasias. Sedation, dry mouth, nasal stuffiness, and postural hypotension may occur.

methyldopa

An alpha adrenergic agonist drug that, paradoxically, is effective in the treatment of high blood pressure (HYPERTENSION). The drug is said to act centrally on the brainstem by stimulating adrenergic receptors in such a way as to reduce the normal action of the sympathetic nervous system on arteries. This explanation is not universally accepted. The drug is on the WHO official list. A brand name is Aldomet.
References in periodicals archive ?
Nonstress tests were reactive in 84% of 76 patients on labetalol and in 81% of 36 patients on methyldopa, a difference that was not statistically significant, reported Dr.
One hundred and six subjects (50 from continuous, 56 from control) had dropped out because of non-compliance, unfavourable responses to methyldopa and exercise training or had incomplete data; therefore, only the data for 217 subjects were used in the statistical analysis (figure 1).
Alpha methyldopa in the treatment of hypertenstion.
Methyldopa is the first-line agent of choice to treat hypertension in pregnancy and has a well-documented safety profile, [33,34] while the calcium channel blocker, nifedipine, [35] and the selective [[alpha].
Historically, DIIHA was described to occur with methyldopa and high-dose penicillin administration.
Admission medications included methyldopa 500 mg twice daily, progesterone 200 mg at bedtime, prenatal vitamin daily, folic acid 0.
Catapres, Catapres-TTS-1, Catapres-TTS-2, Duraclon), methyldopa (e.
In an hypothesis-generating historical cohort study conducted in the Netherlands, the authors identified 202 singleton children born in 1 of 12 hospitals between 1983 and 1987, whose mothers had developed pregnancy-induced or pregnancy-aggravated hypertension and were treated with either methyldopa (61), labetalol (58), or bed rest (83).
She took methyldopa for pregnancy-induced hypertension and had a family history of subarachnoid haemorrhage.
August suggesting switching to a safer agent (such as methyldopa or labetalol) as soon as a patient misses her menstrual period.
You can take action as well, by eating right, exercising, avoiding sunlight, getting plenty of rest and avoiding certain drugs (such as chlorpromazine, hydralazine, isoniazid, methyldopa and procainamide), which may trigger lupus flares.
These substances include cardiovascular drugs, anticancer agents, hormones, psycho-tropics, anti-inflammatory and anti-infective agents, sedatives, anti-Parkinsonian drugs, alcohol and other addictive substances, and antihypertensives (reserpine, methyldopa, propanolol hydrochloride, guanethidine sulfate, hydralazine hydrochloride, clonidine hydrochloride, and diuretics), to name a few.