methyldopa


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methyldopa

 [meth″il-do´pah]
a phenylalanine derivative administered orally or intravenously as an antihypertensive agent.

methyldopa

/meth·yl·do·pa/ (-do´pah) a phenylalanine derivative used in the treatment of hypertension.

methyldopa

(mĕth′əl-dō′pə)
n.
A drug, C10H13NO4, used to treat hypertension.

methyldopa

[-dō′pə]
an alpha2 receptor agonist that acts in the central nervous system to decrease sympathetic nervous system outflow.
indications It is prescribed for the reduction of hypertension in moderate to severe cases.
contraindications Use of monoamine oxidase inhibitors, liver dysfunction, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are liver toxicity and blood dyscrasias. Sedation, dry mouth, nasal stuffiness, and postural hypotension may occur.

methyldopa

An alpha adrenergic agonist drug that, paradoxically, is effective in the treatment of high blood pressure (HYPERTENSION). The drug is said to act centrally on the brainstem by stimulating adrenergic receptors in such a way as to reduce the normal action of the sympathetic nervous system on arteries. This explanation is not universally accepted. The drug is on the WHO official list. A brand name is Aldomet.
References in periodicals archive ?
A comparison of no medication versus methyldopa or labetalol in chronic hypertension during pregnancy.
At the end of the 8 weeks, all subjects were asked to stop methyldopa and were prescribed placebo tablets in a single blinded method for a week to wash out the effect of the methyldopa.
Children in the labetalol group were also more likely to exhibit these behaviors than were children in the methyldopa group but not significantly so (OR, 2.
Attending physicians should feel comfortable using labetalol or methyldopa for pregnant patients with hypertension.
The results showed that around twice as many children exposed to labetalol had attention deficit hyperactivity disorder (ADHD) than those exposed to methyldopa.
All decongestants can interact adversely with monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, indomethacin, beta blockers, methyldopa, some general anesthetics, digitalis, antihypertensives, rauwolfia alkaloids, other central nervous system (CNS) stimulants, and possibly theophylline.
Q I HAVE had high blood pressure for 30 years and have been on methyldopa and frusemide.
Among the products, which are generally sold under private labels are: albuterol tablets, alprazolam tablets, amoxicillin capsules and oral suspension, atenolol tablets, captopril tablets (tentative approval pending patent expiration), cephalexin capsules and oral suspension, cimetidine tablets, clofibrate capsules, flurbiprofen tablets, indomethacin capsules, loperamide capsules, methyldopa tablets, metoprolol tablets, mexiletine capsules, naproxen and naproxen sodium tablets, nifedipine capsules, pindolol tablets, piroxicam capsules, timolol maleate tablets, and tolmetin sodium capsules and tablets.
Removal of drugs that contribute to depression is essential; these include commonly used antihypertensives, such as methyldopa, beta blockers, reserpine, and the other sympatholytics.
In many instances, serum drug levels are unavailable, such as for antihypertensive diuretics, methyldopa, many cardiac agents, anticoagulants, H.