methylate

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methylate

[meth´ĭ-lāt]

1. a compound of methyl alcohol and a base.

2. to add a methyl group to a substance.

meth·yl·ate

(meth'i-lāt),

1. To mix with methanol.

2. To introduce a methyl group.

3. A compound in which a metal ion methyl replaces the alcoholic hydrogen of alcohol.

References in periodicals archive ?

Although the bacterial homologs of N6AMT1 have been shown to methylate DNA N6-adenine (Stephens et al.

The UROtsa cell line, originally isolated from a primary culture of normal human uroepithelium, does not methylate arsenic because of the absence of AS3MT expression (Drobna et al.

Although these data suggest that AS3MT plays a critical role in arsenic methylation and toxicity, a recent study showed that As3mt-knockout mice retain some ability to methylate arsenicals, suggesting the existence of other methyltransferases that could be involved in alternative arsenic metabolism pathways (Drobna et al.

In this study, we found that N6AMT1 has the capacity to methylate [MMA.sup.III] to DMA.

Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity