methsuximide

methsuximide

 [meth-suk´sĭ-mīd]
an anticonvulsant used in the treatment of petit mal epilepsy; administered orally.

methsuximide

An antiepileptic used for absence seizures/petit mal epilepsy.

Adverse effects
Confusion, dizziness, drowsiness, headache, stomach ache, incoordination, anorexia, weight loss, nausea, vomiting, constipation, diarrhoea, insomnia.

methsuximide

Celontin® Neurology An antiepileptic used for absence seizures/petit mal epilepsy. See Therapeutic drug monitoring.
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In contrast, first-generation AEDs that do not appear to be associated with a significant risk of birth defects include the benzodiazepines (clonazepam [Klonopin], clorazepate [Tranxene], diazepam [Valium], and lorazepam [Ativan]) and succinimides (ethosuximide [Zarontin] and methsuximide [Celontin]).
Other drugs assayed at therapeutic concentrations that had no interference included carbamazepine and its epoxide and hydroxy metabolites, oxcarbazepine and it monohydroxylated metabolite, zonisamide, levetiracetam, phenytoin and its metabolites, felbamate, lamotrigine, clonazepam, phenobarbital, primidone, acetaminophen, salicylate, ibuprofen, amitriptyline, nortriptyline, desipramine, doxepin and nordoxepin, imipramine, valproic acid, topiramate, mephenytoin and Nirvanol, amiodarone and desethylamiodarone, methsuximide and normethsuximide, ethotoin, clozapine, and sertraline.
Classification and Pharmacologic Management of Seizures Seizure First Line Agents New/Alternative Agents Simple Partial phenytoin primidone carbamazepine phenobarbital valproic acid gabapentin lamotrigine felbamate topiramate ethotoin mephenytoin Complex partial phenytoin primidone carbamazepine valproic acid phenobarbital mephobarbital gabapentin lamotrigine felbamate topiramate amobarbital Absence clonazepam methsuximide ethosuximide phensuximide valproic acid lamotrigine trimethadione Myoclonic valproic acid clonazepam Tonic Clonic phenytoin/fosphenytoin phenobarbital carbamazepine primidone valproic acid topiramate Stares epilepticus phenytoin/fosphenytoin diazepam lorazepam phenobarbital diazepam secobarbital pentobarbital