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Related to methoxychlor: Malathion


An insecticide resembling DDT; ectoparasiticide.
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Trans-nonachlor, o,p,-DDD, p,p'-DDD, endosulfan I, endrin, and methoxychlor were also associated with significantly reduced number of eosinophils by 24-49%, while p,p'-DDT, o,p'-DDE, and p,p'-DDE were related with 9-16% reduction in monocyte count.
It is worth noting that all single-adjustment model EADs for the known proestrogen, methoxychlor (Hu and Kupfer 2002), were within 1 log of the observed LEL values for both oral and injection studies, indicating that the in vitro assays were able to sufficiently characterize this chemical's estrogenic properties.
The greatest mean values were measured for MeHg (1100 [micro]g x [kg.sup.-1]) and [summation]-DDX (600 [micro]g x [kg.sup.-1]), followed by methoxychlor (240 [micro]g x [kg.sup.-1]), [summation]-chlordane (72 [micro]g x [kg.sup.-1]), heptachlor (70 [micro]g x [kg.sup.-1]), [summation]-HCH (54 [micro]g x [kg.sup.-1]) and HCB (48 [micro]g x [kg.sup.-1]).
Standard OCPs including pp-DDT, ppDDD, pp-DDE, [alpha] HCH, [gamma] HCH, heptachlor, heptachlor epoxide, aldrin, endrin, chlordane, methoxychlor, and HCB were obtained from Sigma-Aldrich (Germany).
Fiskum, "Effects of the organochlorine pesticide methoxychlor on dopamine metabolites and transporters in the mouse brain," Neurotoxicology, vol.
The mixed standard of OCPs (methoxychlor, [alpha]-endosulfan, [beta]-endosulfan, [alpha]-, [beta]-, [gamma]-, and [delta]-hexachlorocyclohexane (HCH), heptachlor, dieldrin, aldrin, endrin, endosulfan sulphate, p,p'-DDE, p,p'-DDD, p,p'-DDT, and gamma-chlordane) was obtained from Supelco (PA, USA).
The commercially available pure active metabolites of methoxychlor and flutamide (HPTE and 2-hydroxyflutamide, respectively) were also tested in parallel to both compare the difference observed between the pure metabolite and the metabolite mixture generated by the S9, as well as to investigate whether the known active metabolite is itself a substrate for further metabolism.
Low-dose bioactivity of xenoestrogens in animals: fetal exposure to low doses of methoxychlor and other xenoestrogens increases adult prostate size in mice.
Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline.
In all, eleven pesticides (diazinon, chlorpyrifos, dimethoate, methoxychlor, malathion, aldrin, cyfluthrin, permethrin, fenvalerate, endosulfan, and DDT) were detected in the honey samples (Table 1).