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Related to methicillin: oxacillin, vancomycin


a semisynthetic penicillin that is highly resistant to inactivation by penicillinase; its sodium salt is used parenterally as an antibacterial.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


A semisynthetic penicillin, C17H20N2O6S, formerly used in the form of its sodium salt to treat infections caused by penicillinase-producing staphylococci.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

Patient discussion about methicillin

Q. My father was hospitalized for pneumonia. The doctors said they are afraid of HA-MRSA. Why is it so scary? My father was hospitalized for pneumonia last week. The doctors wanted to discharge him as quick as possible because they said that they are afraid of Hospital Acquired Methicillin-resistant Staphylococcus aureus (HA-MRSA). Why is it so scary?

A. Hospital Acquired Methicillin-resistant Staphylococcus aureus is a leading cause of sepsis and death due to the fact that are very limited antibiotics that kill it.
Because of this it is the nightmare of doctors.
This bacteria is very durable and is very common in hospitals, and because of it, its always better to be at the hospital the minimum time needed.

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References in periodicals archive ?
Nasal carriage of methicillin resistant Staphylococcus aureus among health care workers at a tertiary care hospital in Western Nepal.
Prolonged hospital stay was a risk factor for methicillin resistance, whereas stay for >25 days was found to be a highly significant risk factor.
A study that was conducted in Pakistan in the department of Microbiology, University of Health Sciences, Lahore to determine the in-vitro activity of linezolid against clinical isolates of methicillin resistant Staphylococci showed that linezolid was effective against all the strains of methicillin resistant Staphylococcus aureus (MRSA) and methicillin resistant coagulase-negative Staphy-lococci (MRCoNS) in the range of 1.0-4.0 mg/L and 0.5-4.0 mg/L MICs, respectively6.
The isolate displayed a [beta]-lactam-resistant phenotype without carrying the methicillin resistance genes mecA or mecC.
The mecA gene was detected in all isolates to confirm the methicillin resistance [14].
Resistance against beta lactamase resistant beta lactams (methicillin) was reported in 1961.
As clinical laboratory standards institute (CLSI) suggested (2011), to confirm the methicillin resistance in the Staphylococcus, we could use the sensitive test to the Oxacillin and Methicillin (9,15,18).
Association between methicillin susceptibility and biofilm regulation in Staphylococcus aureus isolates from device-related infections.
aureus (MSSA) by exogenously acquisition of methicillin resistance gene carried out by a mobile genetic element known as staphylococcal cassette chromosome i.e.

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