methaqualone


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Related to methaqualone: Benzodiazepines

methaqualone

 [meth″ah-qua´lōn]
a nonbarbiturate compound formerly used as a sedative and hypnotic; now found only as a drug of abuse. See drug abuse.

methaqualone

(mĕth′ə-kwā′lōn′)
n.
A potentially habit-forming drug, C16H14N2O, formerly used as a sedative and hypnotic.

methaqualone

An addictive Schedule-II hypnotic-sedative quinazolone with barbiturate-like effects which, when it was legal, was used to reduce anxiety and tension. It was a popular drug of abuse, and it was linked to physical or psychologic dependence.

Clinical findings
Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anaemia.
 
Route
Oral, injected, sniffed, smoked.
 
Management of overdose
Haemoperfusion.

Toxic range
> 8 µg/mL, serum; > 300 µg/L, urine.
 
T1/2
20–60 hours.
 
Specimen
Serum, random urine.
 
Method
GC.

methaqualone

Quaalude, 'ludes' Substance abuse An addictive Schedule II hypnotic-sedative quinazolone with barbiturate-like effects; methaqualone was a popular drug of abuse and linked to physical or psychologic dependence Clinical Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anemia Route Oral, injected, sniffed, smoked Used for Anxiety, tension Management Hemoperfusion. See Controlled drug substance.
References in periodicals archive ?
Alcohol was detected in combination with one or more illicit drugs in 36.4% of our study cases, with the highest BAC recorded being an exceptionally high level of 0.47 g/100 mL, present in a victim who also tested positive for cannabis and methaqualone (a combination suggesting the use of what is colloquially referred to as 'white pipe').
For example, if it is alleged that the defendant intended to sell heroin but actually sold methaqualone, instructions on elements 1 and 2 below would be given.
The participant volumes suggest that LSD and methaqualone testing may not be necessary, except in specific geographic locations, such as the South and Midwest, where abuse ratesmay be higher.A laboratory'sDAUpanel should reflect abuse rates in that area.
In Mastrangelo, the defendant was charged along with eleven co-defendants with crimes stemming from the importation of large amounts of marijuana and methaqualone tablets.
After these drugs were demonized, DeGrandpre notes, psychoactive pharmaceuticals such as meprobramate (Miltown), amphetamines (Benzedrine, Dexedrine, Methedrine), barbiturates (Ambutal, Nembutal, Seconal), methaqualone (Quaalude), and the benzodiazepines (Librium, Valium, Xanax, Ativan, Halcion) followed "the same cycle of medical hype, vast nonmedical use, and new and 'unexpected' problems of dependency." DeGrandpre argues that SSRI antidepressants such as Prozac are undergoing a similar re-examination.
There is also widespread harvesting of small plots of marijuana and khat, and Kenya serves as a transit nation for heroin and Indian methaqualone (CIA, 2007).
* It has the world's highest consumption of the illegal drug methaqualone
* Rigidity--may be due to hyperthermic conditions (see above) and also think of black widow spider, methaqualone (Mandrax) and phencyclidine (PCP).
Methaqualone was extracted from the toffee samples using 1 molar NaHCO3 solution and an EvidexII solid-phase extraction (SPE) cartridge.
To be exact, evidence showed that Mastrangelo was involved in the importation of 23.4 tons of marijuana and 499,000 methaqualone tablets, Id.