metenkephalin


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en·keph·a·lins

(en-kef'ă-linz),
Pentapeptide endorphins, found in many parts of the brain, that bind to specific receptor sites, some of which may be pain-related opiate receptors; hypothesized as endogenous neurotransmitters and nonaddicting analgesics. Metenkephalin is Tyr-Gly-Gly-Phe-Met; leuenkephalin has Leu in place of Met; proenkephalin has Pro in place of Met.

metenkephalin

One of the several ENDOGENOUS opium-like substances having a sequence of five amino acids. See also ENDORPHINS.
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References in periodicals archive ?
Such peptides were originally synthesized as copies of metenkephalin peptides.
Beta-endorphin, Metenkephalin and corresponding opioid receptors within synovium of patients with joint trauma, osteoarthritis and rheumatoid arthritis.
This project will determine the effect of metenkephalin, Tyr-Gly-Gly (YGG) and Tyr-Gly (YG) on the in vitro production of the cytokine, IL-2.
The affinity of [mu]-opioid-receptor agonists such as morphine; diprenorphine; n-Ala(2),N-MePhe(4),Gly(5)-olenkephalin (DAMGO); [beta]-endorphin; metenkephalin; and dynorphine was not changed, but the potency and efficacy of DAMGO, (3-endorphin, and morphine were decreased (22).