Basosquamous carcinoma and metatypical
basal cell carcinoma: a review of treatment with Mohs micrographic surgery.
Squamous cell carcinoma (20 patients), metatypical
carcinoma (6 patients), and malignant melanoma (2 patients) were the other histopathologic diagnoses among malignant tumors.
BerEP4 was positive within the basaloid tumor cells but negative in metatypical
and intratumoral melanocytes [33, 48].
Aggressive-growth BCC variants, including micronodular, infiltrative, morpheaform, and metatypical
, share features of increased cell necrosis, mitotic activity, and stromal proliferation, with a decreased demonstration of stromal retraction, deeper growth, and less circumscription.
Furthermore, GBCC is characterized by an aggressive histological subtype (morpheaform, micronodular, and metatypical
The latter included the infiltrative, morpheic, micronodular and metatypical
Features of biopsy in diagnosis of metatypical
basal cell carcinoma (Basosquamous Carcinoma) of head and neck.
This carcinoma is also known as metatypical
carcinoma, basaloid squamous cell-carcinoma, and basal squamous cell-epithelioma.4 While the rate of recurrence is low in BCC, BSCC tends to recur.
The histopathological subtypes of BCC in this study were classified into nine major patterns: Nodular, superficial, micronodular, infiltrative, keratotic, morpheaform, metatypical
, adenoid, and infundibulocystic types.
carcinomas with squamous differentiation in histological evaluations were excluded.
For example, keratotic BCC and metatypical
BCC are very similar to basaloid SCC in H and E prepared microscopic
It is a common trend to call such tumors as metatypical
or basosquamous carcinomas.