metastatic


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Related to metastatic: metastatic calcification, metastatic carcinoma, Metastatic disease, Metastatic lesion

met·a·stat·ic

(met'ă-stat'ik),
Relating to metastasis.

metastatic

brain tumor

Neurology A neoplasm affecting the brain which may be 1º–brain or meninges, or 2º–ie metastatic to the brain; malignant gliomas account for 2.5% of all cancer-related deaths; BTs are the 3rd most common CA in ages 15-34; 35,000 BTs occur/yr–US; 1st-degree relatives of children with brain tumors have a 5-fold ↑ in the risk of CNS tumors, leukemia, and other childhood tumors in the affected family Clinical Seizures, vision or hearing loss, hemiparesis, double vision, headache, weird behavior, N&V, memory loss Imaging MRI without and with contrast, CT Management Surgery, gamma knife radiotherapy are often effective; chemotherapy, immunotherapy are not. See Gamma knife.
Brain tumors/masses
Primary
Nonneoplastic
Craniopharyngioma, colloid cysts
Primary–benign
Meningioma, pituitary adenoma, acoustic neuroma, epidermoid tumors, choroid plexus papilloma
Primary–low grade
Pilocytic astrocytoma, astrocytoma, hemangioblastoma, oligodendroglioma, ganglioglioma
Primary–malignant
Anaplastic astrocytoma, glioblastoma multiforme, ependymoma, lymphoma, medulloblastoma, primitive neuroectodermal tumor, germ cell tumor, pineal cell tumor, chordoma, choroid plexus carcinoma
Metastatic
Carcinoma, meningeal carcinomatosis
.

met·a·stat·ic

(met'ă-stat'ik)
Relating to metastasis.

metastasis

(mĕ-tăs′tă-sis) plural.metastases [″ + stasis, stand]
1. Movement of bacteria or body cells (esp. cancer cells) from one part of the body to another.
Enlarge picture
METASTASES: CT scan of liver (upper left) with round metastatic tumors (Courtesy of Harvey Hatch, MD, Curry General Hospital)
2. Change in location of a disease or of its manifestations or transfer from one organ or part to another not directly connected. See: illustration

The usual application is to the manifestation of a malignancy as a secondary growth arising from the primary growth in a new location. The malignant cells may spread through the lymphatic circulation, the bloodstream, or avenues such as the cerebrospinal fluid.

metastatic (mĕt″ă-stăt′ĭk), adjective

Metastatic

The term used to describe a secondary cancer, or one that has spread from one area of the body to another.
Mentioned in: Coagulation Disorders

metastatic

pertaining to or of the nature of a metastasis.

metastatic abscesses
abscesses seeded down in tissues distant from a mother abscess.
metastatic calcification
deposition of calcification in soft tissues, e.g. muscles and connective tissue.
metastatic cascade
the series of events leading to metastasis, starting with detachment of neoplastic cells from the primary site through to attachment and tumor growth at a distant site.
References in periodicals archive ?
People living with metastatic breast cancer often feel isolated, stigmatized and at fault for their diagnosis.
The atypical aspect of this case is that our patient was a female nonsmoker with a relatively small laryngeal tumor who developed late metastatic dissemination to the brain, lungs, and pelvis.
Coverage of the Metastatic Hormone Refractory Prostate Cancer pipeline on the basis of route of administration and molecule type.
It's About Time encourages metastatic breast cancer patients, their families, caretakers and advocacy organizations to engage in a national conversation over the next six weeks about metastatic breast cancer facts, what time means to them, opportunities for increased advocacy and research supporting metastatic breast cancer, and, most importantly, to create a platform for those battling metastatic breast cancer to share their stories.
The NM23 mRNA levels were found to decline in tumors from women with many involved lymph nodes, an indicator of high metastatic potential," she says.
Eisai-sponsored Initiative Further Raises MBC Awareness and Amplifies the Voices of Metastatic Breast Cancer Patients In addition to launching mbcInfoCenter.
In such a case, it is possible that the neck mass itself is the primary tumor or that the neck mass represents a metastatic deposit with spontaneous regression of the primary elsewhere; only four such cases have been described.
To show their support, women living with metastatic breast cancer can upload photos of themselves on social media using the campaign hashtag #MBCStrength.
Tissue specimens were harvested from three sites in each patient--from the primary tumor, from the clinically involved regional metastatic lymph node, and from normal tissue adjacent to the primary tumor.
About one third of women diagnosed with breast cancer will develop metastatic disease and subsequently die from their advanced breast cancer.
Summary GlobalData's clinical trial report, "Metastatic Breast Cancer Global Clinical Trials Review, H1, 2014" provides data on the Metastatic Breast Cancer clinical trial scenario.
The facial lesion was found to be a malignant cystosarcoma phyllodes metastatic to the mandible, and the patient died shortly after diagnosis.