metastases


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metastasis

(mĕ-tăs′tă-sis) plural.metastases [″ + stasis, stand]
1. Movement of bacteria or body cells (esp. cancer cells) from one part of the body to another.
Enlarge picture
METASTASES: CT scan of liver (upper left) with round metastatic tumors (Courtesy of Harvey Hatch, MD, Curry General Hospital)
2. Change in location of a disease or of its manifestations or transfer from one organ or part to another not directly connected. See: illustration

The usual application is to the manifestation of a malignancy as a secondary growth arising from the primary growth in a new location. The malignant cells may spread through the lymphatic circulation, the bloodstream, or avenues such as the cerebrospinal fluid.

metastatic (mĕt″ă-stăt′ĭk), adjective

Metastasis (plural, metastases)

A tumor growth or deposit that has spread via lymph or blood to an area of the body remote from the primary tumor.
Mentioned in: Malignant Melanoma

Patient discussion about metastases

Q. I have met my close friend after 3 years. She is showing some signs of high depression. How can I help her? I have met my very close friend after 3 years and she is very depressed. I am worried that she is showing some signs of high depression. She talks all rubbish and negatives these days which is filled with that nonsense hopelessness. She was fine and going good when I left her and now she is completely negative in her behavior and also very depressed. She is not able to enjoy my company. She had lost her weight and her eyes reflect the bluntness. She keeps silent most of the time. How can I help her?

A. I think first you must talk to her and find out about when and how this started. Take her to all the places where you both used to go. She might have come across difficult phase in these years which would have made her depressed and she may need a support to bring her back to normal way of living. We cannot say that this is a depression which would get cured by just talking and knowing the reasons but you must help her to fight back for the thing she had lost. If there is no desired result, then do consult a physician.
http://www.youtube.com/watch?v=P9QxddJOQY4&eurl=http://www.imedix.com/health_community/vP9QxddJOQY4_nervous_system_depression_psyche?q=depression&feature=player_embedded

Q. Does staging in breast cancer is linked to metastasis and what is the use of staging?

A. stages in cancer tell of it's progress. is it benign, does it have a capsule, did it metastasized and all that. but if you are looking for more accurate and more information on that in general:
http://www.breastcancer.org/symptoms/diagnosis/staging.jsp

this should do it!

Q. What is the best pathophysiology of colorectal cancer. The pathophysiology just has to be brief and concise. It also has to include nursing considerations for the patient.

A. i'm not sure i understand your question...do you mean what is the best treatment for colorectal cancer? patophysiology is the changes the tissue acquired. if you'll give me more details on what you are looking for i'll be more then happy to help you.

More discussions about metastases
References in periodicals archive ?
After curative surgical resection of primary rectal cancer, if patients develop hepatic metastasis the chances of curative treatment still exist and it depends upon the disease status, its extent and available treatment options.16-18 During the past two decades, the five-year survival rates for hepatic rectal metastases patients have almost doubled from 30% to 60%.1 9
Kisqali plus endocrine therapy demonstrated consistent efficacy across the MONALEESA trials in patients with and without visceral metastases. In patients with visceral metastases and measurable disease, the overall response rate (ORR) in patients who received Kisqali plus endocrine therapy compared to endocrine therapy alone was 53% vs 40% (MONALEESA-2), 50% vs 38% (MONALEESA-7) and 48% vs 31% (MONALEESA-3).
These patients showed peritoneal carcinomatosis, liver, ovarian, adrenal, and uterine metastases (with or without extra-abdominal metastases).
Sonographic evaluation of clinically occult in-transit and satellite metastases from cutaneous malignant melanoma.
Radiation therapy for the management of painful bone metastases: Results from a randomized trial.
"But what if that particular mutation is only present in some of the metastases of the patient?" Only the metastases composed of cells with mutation X would respond to treatment and shrink or go extinct; those without mutation X would continue to grow.
Cutaneous metastases in patients with metastatic carcinoma: a retrospective study of 4020 patients.
The results suggest that the current staging systems "distinguished poorly to moderately between patients who developed metastases and those who did not," Dr.
Metastases were located on the left side (n=5), on the right side (n=4), or on both sides (n=1) (Table 1).
Lytic bone metastases are due to a variety of primary tumors and are more common than sclerotic metastases [5].
Skeletal muscle metastases are uncommon and usually discovered at autopsy with studies suggesting an incidence as low as 0.8-1.6% [2, 3].