His medications included theophylline, prednisone, inhaled beclomethasone dipropionate and metaproterenol
sulfate, verapamil hydrochloride, oxybutynin chloride, ophthalmic dipivefrin hydrochloride, and topical metronidazole.
Metered-dose inhaler Albuterol (Ventolin, Proventil) Epinephrine (Medihaler-Epi, Primatene Mist) Isoethadne (Bronchometer) Isoproterenol (Isuprel Medihaler) Isoproterenol and phenylephrine (Duo-Medihaler) Metaproterenol (Metaprel, Alupent) Pirbuterol (Maxair) Salmeterol (Serevent) Terbutaline (Breathair)
Nebulizer solutions Albuterol (Ventolin) Metaproterenol (Metaprel, Alupent) Terbutaline (Brethair)
nebulization: a bacteriologic survey.
Fiscal year sales and earnings were also boosted by sales of other new products approved during the 1992 calender year, including cinoxacin, baclofen, minocycline and metaproterenol
Widespread harm from OTC ibuprofen and hydrocortisone was predicted, yet both have been used safely, and hydrocortisone alone has saved an estimated $600 million dollars in its first 2 years of reclassification. On the other hand, the FDA withdrew metaproterenol
's OTC status because of "post change" safety concerns.
The company also received FDA approval to market baclofen tablets, the generic equivalent of Geigy Pharmaceuticals' Lioresal, and metaproterenol
sulfate syrup, the generic form of Boehringer Ingelheim Inc.'s Alupent syrup.
In 1987 Dey was the first manufacturer to receive Food and Drug Administration approval for a unit-dose metaproterenol
sulfate inhalation solution.
Therapeutic Agents Available in Metered Dose Inhaler Duration Average Peak of Cost per Pregnancy Effect(*) Effect(*) Inhaler(**) Category Drug (minutes) (hours) ($) (FDA) [beta]-Adrenergic Isoproterenol 5-15 1-2 23.63 C Isoetharine 15-60 2-3 26.98 C Metaproterenol
30-60 3-4 20.23 C Terbutaline 60 4 22.10 B Albuterol 30-60 4 24.16 C Bitolterol 30-60 5 18.00 C Pirbuterol 30-60 5 18.82 C Anticholinergic Ipratropium 60-120 3-6 26.80 B Biscromones Cromolyn 15-30 2-6 37.15 B (*)Data from Physicians' Desk Reference, Drug Evaluations, and Bar-Yish ay et al. (**) Derived from pharmacy price quotes.
They also cite cases in which such drugs as metaproterenol
were given O-T-C status - then returned to sale by prescription only after they proved unsafe for O-T-C consumption.