metaphase


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metaphase

 [met´ah-fāz]
the second stage of cell division (mitosis or meiosis), in which the chromosomes, each consisting of two chromatids, are arranged in the equatorial plane of the spindle prior to separation.

met·a·phase

(met'ă-fās),
The stage of mitosis or meiosis in which the chromosomes become aligned on the equatorial plate of the cell separating the centromeres. In mitosis and in the second meiotic division, the centromeres of each chromosome divide and the two daughter centromeres are directed toward opposite poles of the cell; in the first division of meiosis, the centromeres do not divide but the centromeres of each pair of homologous chromosomes become directed toward opposite poles.
[meta- + G. phasis, an appearance]

metaphase

(mĕt′ə-fāz′)
n.
The stage of mitosis and meiosis, following prophase and preceding anaphase, during which the chromosomes are aligned along the metaphase plate.

metaphase

A stage in mitosis or meiosis during which the chromosomes align along the equatorial plate of the cell and kinetochores contact the microtubuli of the spindle apparatus. The chromosomes are most condensed and best studied by classic cytogenetics during metaphase.

met·a·phase

(met'ă-fāz)
The stage of mitosis or meiosis in which the chromosomes become aligned on the equatorial plate of the cell separating the centromeres. In mitosis and in the second meiotic division, the centromeres of each chromosome divide, and the two daughter centromeres are directed toward opposite poles of the cell; in the first division of meiosis, the centromeres do not divide, but the centromeres of each pair of homologous chromosomes become directed toward opposite poles.
[meta- + G. phasis, an appearance]

metaphase

Stage of MITOSIS or MEIOSIS during which the chromosomes are aligned around the equator of the cell and are visible on microscopy. The stage at which the banding pattern of the chromosomes is apparent.
Metaphaseclick for a larger image
Fig. 220 Metaphase . Position of chromosomes in mitosis and meiosis.

metaphase

a stage of nuclear division in EUKARYOTE cells, occurring once in MITOSIS and twice in MEIOSIS. The main process involved is the organization of CHROMOSOMES at the equator of a spindle, forming a metaphase plate. Each chromosome is divided into two CHROMATIDS, joined at a CENTROMERE. The chromosomes are densely staining and highly condensed, properties which makes them suitable for the production of KARYOTYPES. The spindle MICROTUBULES become attached to an area of the centromere called the kinetochore, the precise arrangement of chromosomes appearing to be random (this has important genetic implications, see INDEPENDENT ASSORTMENT) and different in mitosis and meiosis (see Fig. 220 ). The metaphase plate in the second cycle of meiosis is at right angles to the equator in metaphase I.
References in periodicals archive ?
Conversely, the oocyte at metaphase II develop into a size of 15-20 mm.
Metaphase's visible NIR light, for example, uses five LEDs: a broadband blue LED emitting from 400nm to 500nm; a broad white LED for up to around 700nm; and then three different LEDs to cover the 700nm to 1,000nm range.
Figure 1A-D shows a zygote at metaphase of the first meiosis viewed from the lateral side.
The usual guidelines of metaphase analysis were followed with minor adjustments to identify an abnormal clone: at least 4 of 20 cells for both structural and numerical abnormalities.
Cell cycling was arrested in metaphase by addition of 10 [micro]g/ml colcemid and incubating for 2-4 hours (Thermo Fisher Scientific[R], Paisley, UK).
Metaphase FISH analysis revealed normal karyotypes for both parents, with no genetic duplication in either the 7p22.1p21.1 or the 15q24.1 region, suggesting that the duplications identified in the fetus were de novo in origin.
Mitotic metaphase cells of Micropholcus piaui and Micropholcus ubajara (Pholcinae) present 2n[male] = 9 (Fig.
Figure 1 shows the ovarian maturational status parameters (germinal vesicle, metaphase I and/or metaphase II) in rats following 14 days of treatment with co-trimoxazole, folic acid, and their combination.
FISH employs fluorescently-labeled DNA probes to bind complementary DNA sequences within an interphase cell, or onto metaphase chromosomes.
Photomicrograph slide of kidney cells showing (a) normal metaphase without chromosome B; (b) normals metaphases with chromosome B; (c) chromosome stickiness; (d) endomitosis; (e) gaps; (f) breaks; (g) chromosome fragments, and (h) pulverization of P.
Ag-NOR staining to reveal the active NORs in metaphase chromosomes was carried out as described by Stack et al.
The most frequent chromosome aberrations were observed during metaphase, highlighting the occurrence of sticky chromosomes (Fig.