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a urinary metabolite of epinephrine.
A catabolite of epinephrine found in the serum, urine and in some tissues, resulting from the action of catechol-O-methyltransferase on epinephrine; has no sympathomimetic actions; 3-O-methylepinephrine.
metanephrineAny exogenous or endogenous catecholamine metabolite excreted in the urine (normal adults, 0.03–0.69 mmol/mol creatinine). Metanephrines are elevated in neuroblastoma, pheochomocytoma, metastases, stress and sepsis.
False positive elevation
High dietary intake of bananas, or therapy with chlopromazine, corticosteroids, l-dopa, dopamine, guanethidine, hydralazine, imipramine, nalidixic acids, phenobarbital, phenylephrine, or tetracycline.
False negative reduction
Clonidine, guanethidine, propranolol, reserpine.
24–288 µg/24 hours; US, 0.05–1.2 mg/24 hours.
metanephrineMethoxyepinephrine Lab medicine Any exogenous or endogenous catecholamine metabolite excreted in the urine; metnephrines ↑ in neuroblastoma, pheochomocytoma, metastases, stress, sepsis
A metabolite of epinephrine, excreted in the urine and found in some tissues.
A catabolite of epinephrine found in the serum, urine, and some tissue types, due to action of catechol-O-methyltransferase on epinephrine.