Metanephric stromal tumor: report of 31 cases of a distinctive pediatric renal neoplasm.
The most common tumors that may be misclassified as papillary RCCs are the following:
metanephric adenoma, epithelial-predominant nephroblastoma, (33) clear cell RCC with prominent papillary growth pattern, clear cell papillary RCC, and translocation RCC.
During the growth of the embryo, the
metanephric mesoderm, initially located near the cloaca, gradually ascends to a more cephalad position, in the retroperitoneal area; as such, the blood supply will directly be from the aorta, whereas the more caudal supplying branches vanish.
Gene expression profiles in developing nephrons using Lim1
metanephric mesenchyme-specific conditional mutant mice.
The development of the mammalian kidney is guided by reciprocal inductive interactions between the ureteric bud (UB, giving rise to the collecting duct system) and the
metanephric mesenchyme (giving rise to all other renal epithelial cells) [13].
BRAF mutations in
metanephric adenoma of the kidney.
Since Grobstein introduced the transfilter culture of
metanephric mesenchymal cells in 1953 (2), membrane filters have proven to be an invaluable tool in experimental cell biology.
It is challenging to differentiate MTSCC from other renal cell carcinoma subtypes that exhibit comparable morphologic features, but have a less favorable prognosis--namely papillary renal cell carcinoma, collecting duct carcinoma,
metanephric adenoma or sarcomatoid carcinomas.
It's thought to come from very specialised cells in the embryo known as
metanephric blastema.
It lacks discrete cortical and medullary zonation and the loop of Henle of the
metanephric kidney of birds and mammals, which allow these animals to produce hypertonic urine (Hickman and Trump, 1969).
Mean epithelial height of the columnar cells of the proximal tubules, that were PAS positive was 12.44 [+ or -] 0.25 [micro]m in the
metanephric tissue.
(x) the lectin receptors have been reported to be present on the luminal surface of the mesonephric and the
metanephric tubules of human embryos [57] and the distal and collecting tubules of the normal adult kidney [64, 65];
