metamyelocyte

[met″ah-mi´ĕ-lo-sīt″]

a precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and the mature, segmented (polymorphonuclear) granular leukocyte, and having a U-shaped nucleus.

met·a·my·el·o·cyte

(met-ă-mī'el-ō-sīt),

A transitional form of myelocyte with nuclear construction that is intermediate between the mature myelocyte (myelocyte C of Sabin) and the two-lobed granular leukocyte.

Synonym(s): juvenile cell

[meta- + G. myelos, marrow, + kytos, cell]

Farlex Partner Medical Dictionary © Farlex 2012

metamyelocyte

A cell similar in shape, but slightly smaller (10 to 16 µm in diameter) than a myelocytes, which has a central or eccentric, indented kidney bean nucleus. The chromatin is usually coarsely clumped, and there is no nucleolus; the N:C ratio is 1.5:1 to 1:1. The abundant, pink or colourless cytoplasm may contain rare reddish-purple azurophilic (primary) granules and/or many fine, lilac, neutrophilic (secondary/specific) granules.

The metamyelocyte corresponds to the M5 stage of a maturing granulocyte, which is morphologically between a myelocyte (M3 or M4) and a PMN (M6 or M7).

met·a·my·e·lo·cyte

(met'ă-mī'ĕ-lō-sīt)

A transitional form of myelocyte with nuclear construction that is intermediate between the mature myelocyte (myelocyte C of Sabin) and the two-lobed granular leukocyte.
Synonym(s): juvenile cell.

[meta- + G. myelos, marrow, + kytos, cell]

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

References in periodicals archive ?

Number Percentage of cases of cases (%) Peripheral blood smear Monocytosis 05 18.5 Nucleated RBC 06 22.2 Bone marrow aspirate cytology Plasma cells with abnormal inclusions 04 14.8 Dysmyelopoiesis 01 3.7 Eosinophilia 04 14.8 Free floating cytoplasm With LD bodies 01 3.7 Without LD bodies 04 14.8 Intracellular LD bodies in cells other than histiocytes (polymorph, 02 7.4 metamyelocyte, and megakaryocyte) Bone marrow biopsy (total 19 cases) Necrosis 02 10.5 Granuloma 01 5.2 TABLE 4: Atypical bone marrow findings observed in leishmaniasis.

Visceral leishmaniasis with associated common, uncommon, and atypical morphological features on bone marrow aspirate cytology in nonendemic region

Megaloblastic Anaemia- Megaloblasts, Giant Stab and Metamyelocyte in BM Aspirate (100x)

PANCYTOPENIA- A CLINICO-HAEMATOLOGICAL STUDY

The positive smear result was defined as per the International Consensus Group criteria, which included RBC morphology at 2+ or greater, malaria, giant PLTs at moderate or greater, PLT clumps at greater than rare/occasional, Dohle bodies/ toxic granulation/vacuoles at moderate or greater, blasts at 1 or greater, metamyelocytes at greater than 2, myelocytes/promyelocytes at 1 or greater, atypical lymphocytes at greater than 5, NRBCs at 1 or greater, or plasma cell at 1 or greater.

Validation and optimization of criteria for manual smear review following automated blood cell analysis in a large university hospital

(8) Positive smears were determined following the criteria of the consensus group: red blood cell (RBC) morphology of either 2+/moderate or greater; any positive finding related to malaria; platelet morphology (giant platelets) of either 2+/moderate or greater; platelet clumps more frequent than rare/occasional; Dohle bodies, toxic granulation, or vacuoles of either 2+/moderate or greater; and presence of abnormal cell types (blast [greater than or equal to]1, metamyelocyte >2, myelocyte/ promyelocyte [greater than or equal to]1, atypical lymphocytes >5, nucleated RBC [greater than or equal to] 1, and plasma cells [greater than or equal to]1).

Comparison study of the rates of manual peripheral blood smear review from 3 automated hematology analyzers, Unicel DxH 800, ADVIA 2120i, and XE 2100, using International Consensus Group guidelines

33) patients had dysmyelopoeisis which included abnormal shaped nuclei, folded, cleaved nuclei, giant metamyelocyte, myelocyte, pseudo pelger heut anomaly, vacuolisation of the cells and maturation arrest.

A study of bone marrow changes in human immunodefeciency virus infection

Counts: Neutrophils: 61, Lymphocyte: 07, Monocyte: 06, Eosinophil: 05, Basophils: 04, Band forms: 03 Metamyelocyte: 04, Myelocyte: 04, Blast: 06, Platelets count: 4 Lakhs/Cu mm.

A case report: imatinib induced hepatotoxicity in chronic myelogenous leukemia

The blood cell count showed anemia and thrombocytopenia with the following indexes: hemoglobin, 8.7 g/dL; platelets, 23 x [10.sup.9]/L; white blood cells, 6.7 x [10.sup.9]/L; white blood cell differential: segmented neutrophils, 40%; bands, 34%; lymphocytes, 8%; monocytes, 8%; metamyelocytes, 3%; myelocytes, 3%; and nucleated red blood cells, 4%.

Myelophthisis as a Solitary Manifestation of Failure From Rectal Carcinoma A Batson Phenomenon?

It was not found the presence of basophils, atypical lymphocytes, myelocytes, metamyelocytes, blasts in farm workers.

Effects of pesticides on rural workers: haematological parameters and symptomalogical reports/Efeitos dos pesticidas sobre trabalhadores rurais: parametros hematologicos e relatos sintomatologicos

* Immature granulocytes (includes promyelocytes, myelocytes, metamyelocytes)

Advanced clinical parameters: achieving efficiency with automated immature granulocyte count

Laboratory investigations showed haemoglobin 5.7gm./dl; Total leukocyte count 614.8x10 9 /l, Myeloblast 65%, Promyelocytes 10%, Myelocytes 26%, Metamyelocytes 18%, Band cells 4%, Neutrophils 30% and Lymphocytes 7%: ESR 2mm, platelets 709x10 12 /L.

Chronic myeloid leukaemia presenting as priapism: A case report from Khyber Pakhtunkhwa

The patient's complete blood count revealed a hemoglobin of 10.2 g/dL, hematocrit of 33% and platelets of 357 x [10.sup.9]/L, and a corrected WBC count due to the presence of nucleated red blood cells of 60.7 x [10.sup.9]/L including 50% neutrophils, 19% lymphocytes, 10% bands, 7% myelocytes, 7% metamyelocytes, 1% promyelocytes, 5% monocytes, and 1% blasts.

Treatment of metabolic abnormalities with rasburicase in a premature neonate

His initial labs were also notable for an elevated white blood cell count of 51k/cumm (normal 6-18), with 38% bands, 5% myelocytes, and 8% metamyelocytes, an ammonia of 211mCmol/L (normal 11-35), and a lactate of 1.8mmol/L (normal 0.5-1.6).

Food Protein-Induced Enterocolitis Syndrome Causing Hypovolemic Shock and Methemoglobinemia

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