Xanthine oxidase (XO, EC: 188.8.131.52) is a complex metalloflavoprotein
. This enzyme catalyzes the oxidation of hypoxanthine to xanthine and produces uric acid which leads to many diseases like gout and hyperuricemia .
XOR is a dimeric metalloflavoprotein
comprising two identical subunits of approximately 145 kDa each, including one molybdenum-containing molybdopterin cofactor (Moco) and one flavin adenine dinucleotide (FAD) cofactor, as well as two nonidentical iron-sulfur redox centers.
The only justification may be the involvement of iron as a component of various flavoproteins (Metalloflavoproteins
) active in biological oxidation (Devlin and Witham, 1983), which may increase as result of inoculation with the pathogen/ULCV (Ashfaq et al., 2010).