metalloenzyme


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metalloenzyme

 [mĕ-tal″o-en´zīm]
any enzyme containing tightly bound metal atoms, e.g., the cytochromes.

me·tal·lo·en·zyme

(mĕ-tal'ō-en'zīm),
An enzyme containing a metal (ion) as an integral part of its active structure, for example, cytochromes (Fe, Cu), aldehyde oxidase (Mo), catechol oxidase (Cu), carbonic anhydrase (Zn).

metalloenzyme

/me·tal·lo·en·zyme/ (mĕ-tal″o-en´zīm) any enzyme containing tightly bound metal atoms, e.g., the cytochromes.

metalloenzyme

An enzyme that contains a metal ion, usually held by co-ordinate-covalent bonds on the amino acid side chains, or bound to a prosthetic group (e.g., heme). The metal ions function like coenzymes, imparting activity to the enzymes.

Examples
Alcohol dehydrogenase (zinc), ascorbic acid oxidase (copper), cytochrome (iron), cytochrome oxidase (copper), glutamate mutase (cobalt), glutathione peroxidase (selenium), urease (nickel), and xanthine oxidase (molybdenum).

me·tal·lo·en·zyme

(mĕ-tal'ō-en'zīm)
An enzyme containing a metal (ion) as an integral part of its active structure; e.g., cytochromes (Fe, Cu), aldehyde oxidase (Mo), catechol oxidase (Cu), carbonic anhydrase (Zn).

metalloenzyme (meˈ·t·lō·enˑ·zīm),

n an enzyme containing a metal in its active site.

metalloenzyme

any enzyme containing tightly bound metal atoms, e.g. cytochrome oxidase.
References in periodicals archive ?
These results imply that this PO is a copper-containing metalloenzyme similar to the four marine bivalves C.
Biologically Important Metalloenzymes for Skin Anti-aging Metalloenzyme Function Metal Tyrosinase Tyrosine oxidation Cu, Zn Superoxide Dismutase Superoxide detoxification Cu, Zn, Mn Catalase Peroxide decomposition Fe Matrix Metalloproteases Protein hydrolysis Zn Dopamine Hydroxylase Dopamine conversion Cu Amine Oxidase Elastin, collagen synthesis Cu Cytochrome Oxidase Oxidation Cu Ceruplasmin Oxidation Cu Glutathione Peroxidase Peroxide detoxification Se Glucose Tolerance Factor Glucose metabolism Cr
This includes its world leadership in metalloenzyme inhibition and involves creating a sufficiently broad product portfolio, based on both internal and external opportunities, to optimize the probability of compounds completing development and entering the market.
One scientist who has been studying hyperthermophiles since the mid 1980s is Michael Adams, professor of biochemistry, molecular biology, and microbiology and codirector of the Center for Metalloenzyme Studies at the University of Georgia.
Thompson's sensor uses a metalloenzyme as a sensing transducer to maximize sensitivity, which is necessary in complex media such as sea-water and blood serum.
5] first observed that adenosine deaminase (ADA), a zinc-containing metalloenzyme expressed in high levels by lymphocytes and monocytes, was elevated in PTB.
Some of these important metalloenzyme activating minerals include zinc, iron, copper and selenium.
Copper is part of the metalloenzyme dopamine [beta] hydroxylase, which is necessary for the production of noradrenaline, and increased levels of this enzyme have been reported in hyperkinesis.
Carbonic anhydrase (CA) is a zine metalloenzyme that catalyzes the reversible hydration of carbon dioxide: C[O.