metabolizer


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metaboliser

A person who metabolises; that which metabolises, or helps metabolise, a substance.

metabolizer

A person who metabolizes. See Poor metabolizer.

Patient discussion about metabolizer

Q. How is it possible to have permanent weight loss if dieting slows down metabolism? well, i know that eating less will have the body adjust to the new calorie intake and thus, no further weight loss. So how is it possible to have permanent weight loss if eating less doesn't work? Please give tips and suggestions, people who have successfully lost weight. thanks so much!

A. That is why you need to cycle every few weeks. Change things up and shock your body because it does plateau. But if you challenge yourself every so often you will see results continuously.

Q. How could one boost metabolism by diet? I am aware for long that metabolism is the cause for poor health and fitness.So how could one boost metabolism by diet?

A. Metabolism, if it is not erroneous genetically; then it can be controlled or increased by any diet. What matters is the timing and regularity you feed yourself which uses your hormones and enzymes in your body to do the task they are for. This timing and regularity depends on eating in same time regularly and working and sleeping too. To excite some hormones even if they had switched off their action in body, can be excited by exercise and feeding with small diets in regular short time intervals. To make all this happen, reduce on junk foods, please.

Q. How does coffee affect a diet? does it have an affect on metabolism? on losing weight?

A. Well, coffee can increase and to accelerate the beginning of burning fat during exercise (usually only after 20-30 minutes of exercise), but the overall effect is not that substantial. YOu should remember that it makes your kidney to produce more urine, so you should drink more.

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References in periodicals archive ?
The analysis also showed that patients identified as reduced metabolizers were fivefold more likely to be switched than patients identified as ultra metabolizers, and intermediate metabolizes had a 50% higher switching rate than ultra metabolizers.
Those who were intermediate and poor metabolizers were considered for alternate therapy with chloroquine, artemether, or lumefantrine [3].
VEN appears to be associated with these side effects in a CYP2D6 poor and CYP2C19 intermediate metabolizer. Several studies mentioned in this report have suggested cardiotoxicity associated with VEN overdose and in CYP2D6 poor metabolizers.
TABLE 2 Frequencies (%) of CYP2C9 alleles and phenotypes predicted from genotype in different Costa Rican ethnic groups Self-reported Ancestry n *1 *2 *3 *6 gPMs Admixed 137 88.7 7.7 3.6 0.0 0.7 Bribri 46 97.8 1.1 (a) 1.1 0.0 0.0 Cabecar 27 98.1 0.0 (a) 1.9 0.0 0.0 Chorotega 31 95.1 3.2 1.6 0.0 0.0 Guaymi 27 100.0 0.0 (a) 0.0 0.0 0.0 Huetar 48 86.5 8.3 5.2 0.0 0.0 Maleku 15 100.0 0.0 0.0 0.0 0.0 Afro-Caribbean 45 95.6 1.1 (a) 3.3 0.0 0.0 n: number of subjects; gPMs: predicted poor metabolizers from genotype.
Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.
The mother, an ultrarapid metabolizer, was excessively converting the codeine prodrug to the active morphine metabolite.
Moreover, our study showed that the frequency of poor metabolizers in the Turkman ethnic group (10.7%) is relatively close to Thai (9.2%) and Burmese (11%) populations.
Evidence has been presented that persons who are poor metabolizers (PMs) may be at increased risk for dose-related adverse events caused by drugs that are metabolized predominately by CYP2D6, while patients with multiple copies of active genes, UMs, may be more likely to experience therapeutic failure due to rapid metabolism (7).
An extensive metabolizer with recurrent ulcer responding to high dose of lansoprazole.
The mean dextromethorphan and dextrorphan urinary concentrations in addition to the standard deviations (SD) were computed for extensive and poor metabolizer groups independently.
Pharmacogenomic analysis can help identify patients who are abnormally high metabolizers of certain drugs.
(and %) Cases Controls Genotype wt/wt 22 (53.7) 138 (63.6) wt/A 0 5 (2.3) wt/B 10 (24.4) 37 (17.1) wt/C 3 (7.3) 8 (3.7) wt/D 1 (2.4) 5 (2.3) wt/L 0 1 (0.5) wt/L2 2 (4.9) 14 (6.5) B/B 0 6 (2.8) B/C 1 (2.4) 1 (0.5) B/D 0 2 (0.9) C/C 1 (2.4) 0 D/L2(a) 1 (2.4) 0 Expected phenotype(b) Extensive metabolizer Homozygote 29 (70.7) 161 (74.2) Heterozygote 12 (29.3) 48 (22.1) Poor metabolizers 0 8 (3.7) (a) The L2 allele represents an allelic duplication.