metabolite


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Related to metabolite: Secondary metabolite, Primary metabolite

metabolite

 [mĕ-tab´o-līt]
any substance produced during metabolism.

me·tab·o·lite

(mĕ-tab'ō-līt),
Any product or substrate (for example, foodstuff, intermediate, waste product) of metabolism, especially of catabolism.
Synonym(s): metabolin

metabolite

/me·tab·o·lite/ (-līt) any substance produced by metabolism or by a metabolic process.

metabolite

(mĭ-tăb′ə-līt′)
n.
1. A substance produced by metabolism.
2. A substance necessary for or taking part in a particular metabolic process.

metabolite

[mitab′əlīt]
Etymology: Gk, metabole, change
a substance produced by metabolic action or necessary for a metabolic process. An essential metabolite is one required for a vital metabolic process.

metabolite

Physiology
Any substance synthesised or modified by a metabolic process, often understood to mean an intermediate or final product in the breakdown from a parent molecule.

Therapeutics
The transformation of a drug following its metabolism in the body, which results in a different molecule that may be more or less active than the parent drug.

me·tab·o·lite

(mĕ-tab'ŏ-līt)
Any product (intermediate or final, including waste) of a metabolic process.

metabolite

Any substance involved in METABOLISM either as a constituent, a product or a byproduct.

metabolite

any substance used in or a product of METABOLISM.

metabolite

any substance produced during metabolism.
References in periodicals archive ?
They are rapidly metabolised in the liver, and mainly eliminated in the urine as metabolites within 48 hours.
The polar metabolite profiling methods were developed using reference standards of each metabolite to determine chromatographic retention times and MS multiple reaction-monitoring transitions, declustering potentials, and collision energies (see Tables 1-3 in the Data Supplement that accompanies the online version of this report at http://www.
ca), a comprehensive, first-ever public catalog of 4,229 metabolites in human serum.
Center for Epigenetics and Metabolism director Paolo Sassone-Corsi, lead author on the study and one of the world's pre-eminent researchers on circadian rhythms, said the liver metabolites reveal how the body clock - through the main circadian gene, CLOCK - orchestrates the interplay between metabolites and signalling proteins in much the same way a conductor leads a symphony.
The positive test was caused by one of the metabolites of the banned substances showing up in the sample in sufficient quantity.
The development of high resolution, high mass accuracy and high sensitivity LC-MS technologies has been critical to improving the identification of metabolite peaks from background matrix ions.
Linearity of absorbance of venalafaxine metabolite was determined in the range of 0.
Symyx Metabolite provides comprehensive coverage of xenobiotic transformations and metabolic schemes from respected published sources, as well as non-proprietary metabolism studies from new drug applications published by the US Food and Drug Administration.
Accordingly, they concluded that the metabolite helps suppress the progress of osteoporosis.
The third residual metabolite of AF in the liver was 5-OH-AAF, but most of 5-OH-AAF was eliminated by the urine and stool.
The purpose of this project was to find a more direct source for detecting drug metabolites by using human hepatic cells.
Jindal, nephrology) that CYA metabolite profiles of cardiac and renal transplant patients tend to differ.