metabolic diseases


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Related to metabolic diseases: metabolic syndrome, diabetes mellitus, diabetes

metabolic diseases

diseases due to abnormal tissue metabolism, e.g. diabetes mellitus, metabolic bone disease

metabolic

pertaining to internal metabolism.

metabolic acidemia
acidemia due to metabolic error.
metabolic bone disease
includes a range of bone diseases associated with metabolic diseases, e.g. secondary hyperparathyroidism, rickets and osteoporosis.
metabolic defect
generally an inherited defect that is present at birth, but which is not necessarily evident clinically for several months afterwards. The defect creates a metabolic error, which leads to the accumulation of end products which cause clinical signs, e.g. mannosidosis, porphyria or an exaggerated response from an end-organ, e.g. inherited goiter. See also inborn error of metabolism.
metabolic diseases
diseases in which normal metabolic processes are disturbed and a resulting absence or shortfall of a normal metabolite causes disease, e.g. hypocalcemia in cows, or an accumulation of the end products of metabolism causes a clinical illness, e.g. acetonemia of dairy cows. Many diseases in this group really have their beginnings in a nutritional deficiency state. See also production diseases.
metabolic encephalopathy
many disorders of metabolism can lead to neurologic abnormalities through alterations in electrolytes and acid-base balance, accumulation of endogenous toxins. See also encephalopathy.
metabolic error
see metabolic defect (above).
metabolic inhibition technique
a virus neutralization test in tissue culture in which phenol-red indicator is used to detect the acid metabolic products of actively metabolizing cells or the lack of metabolism when cells are infected and destroyed by the virus.
metabolic laminitis
metabolic myopathies
muscular dystrophies caused by metabolic defects; include systemic glycogenoses, deposits of a PAS-positive glycoprotein, the lipid storage disease of cats caused by carnitine deficiency.
metabolic pathways
groupings of enzymic processes leading to the synthesis or breakdown of carbohydrates, amino acids and lipids.
metabolic polymyopathy
a muscle disease associated with a metabolic disorder, e.g. hyperadrenocorticism.
metabolic polyneuropathy
a disease of the nerves associated with a metabolic disorder, e.g. uremia, diabetes mellitus or hypothyroidism.
metabolic profile
results of a spectrum of tests of metabolic functions.
metabolic profile test
metabolic rate
the rate of energy metabolism in the body. The basal metabolic rate (BMR) is the rate of energy consumption by the body when it is completely at rest.
metabolic syndrome
characterized by hypertension, insulin resistance, an abnormal plasma lipid profile, and obesity.
metabolic toxins
include histamine, other toxic amines, ketone bodies, phenols and cresols from the large intestine, which are normal end-products of metabolism and indigestion but if their normal excretion and detoxication are impeded, cause intoxication. See also toxin.
metabolic water
the water produced in the body by oxidative metabolism of food; it represents 5-10% of the body's water utilization.
References in periodicals archive ?
There are at least 400 different metabolic diseases known and more are being discovered.
CEO of Santhera stated, "Biovitrum is an excellent partner because of its strategic focus on metabolic diseases and specialization in this field.
announced that Genzyme has granted an exclusive worldwide license to Peptimmune to develop and market a Genzyme investigational drug candidate for the treatment of obesity and other metabolic disease indications.
Editorial Note: The findings in this report suggest that, during 1996-2001, undiagnosed metabolic diseases were contributing factors in 1% of unexpected deaths in young children in Virginia.
Clarke has done an amazing task in providing this handy guide of approximately 300 pages on how to diagnose inherited metabolic diseases.
a company harnessing breakthroughs in brown fat biology and insulin sensitization to revolutionize the treatment of metabolic disease, today announced the publication of key preclinical data demonstrating that inhibition of the Transient Receptor Potential Vanilloid (TRPV) family of ion channels - specifically TRPV4 - resulted in activation of brown/beige fat and protection from diet-induced obesity, inflammation and insulin resistance.
Diabetes is a metabolic disease characterized by hyperglycemia that in 2002 affected nearly 9% of U.
Peptimmune is a privately held biotechnology company focused on development of therapeutics for the treatment of autoimmune and metabolic diseases.
Moreover, the agent had no apparent side effect, Hansen reported last month at a meeting on metabolic diseases in Tempe, Ariz.
The report also provides the share of generics in global metabolic diseases as well as in each indication market.
I will test if and how the shifted microbial composition in metabolic diseases is associated with alterations in mucosal AMP production and function.
In this report, we look beyond the dominant and well-documented diabetes sector of the metabolic marketplace to analyze opportunities in niche metabolic diseases.