mestranol


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mestranol

 [mes´trah-nol]
a synthetic estrogen used in combination with a progestational agent as an oral contraceptive.

mestranol

(mĕs′trə-nôl′, -nōl′, -nŏl′)
n.
A synthetic estrogen, C21H26O2, used in combination with a progestin in oral contraceptives.

mestranol

An oestrogen drug, used in combination with a PROGESTOGEN as an oral contraceptive or as a hormone replacement therapy for post-menopausal women. A brand names of a combination with the progestogen NORETHISTERONE is Norinyl-1.
References in periodicals archive ?
Proestrogens, such as mestranol, are known to require metabolic transformation to exert estrogenic effects (Schmider et al.
To help improve the reliability of the test, 100 [micro]g of mestranol is also given daily to stabilize estrogen levels during the testing interval.
In vitro and in vivo genotoxicity evaluation of hormonal drugs V, mestranol. Mutation Research, 322: 173-183.
Of these, 4-nonylphenol (linear) was inactive in all 3 ToxCast[TM] in vitro binding assays (but active in 10 of 11 of the remaining agonist-mode assays), 4-dodecylphenol was inactive in 2 of 3 assays (bovine and mouse), and mestranol was inactive in only 1 (mouse) of 3 ToxCast[TM] assays (see Figure 4).
All combination OCs contain either EE or mestranol. However, a variety of progestins have come into use.
[7] The use of oral contraceptives containing less than 100 [microgram] of either ethinyl estradiol or mestranol has approximately one third the risk of thromboembolism that using those products containing 100 [microgram] or more of the estrogen component has.
Preparation of 9-alpha, 11-xi-tritiated 17-alpha-ethynylestradiol, mestranol, estradiol-alpha-17-beta, and norethindrone.