Characteristically, dense eosinophilic secretions are seen within glandular luminal spaces, similar to that seen within benign mesonephric remnants
(Figure 6, C).
Some reports describe the immunohistochemical investigation of mesonephric remnants
that behave as ectopic endometrium in dogs [18, 19].
On the benign spectrum it has to be differentiated from hyperplasia of mesonephric remnants
. Presence of cytologic atypia and variable architectural patterns favor adenocarcinoma.
(13) In addition, recent reports have shown that PAX8 is expressed in lesions of Wolffian/ mesonephric origin, including mesonephric remnants
, mesonephric hyperplasia, mesonephric adenocarcinoma, and carcinosarcoma.
The following pseudoneoplastic lesions are discussed: (1) reactive/reparative glandular atypia; (2) mitotically active endocervical glands; (3) tubal/tuboendometrioid metaplasia; (4) endometriosis; (5) mesonephric remnants; (6) intestinal metaplasia; (7) Arias-Stella reaction; and (8) atypical oxyphilic metaplasia.
Mesonephric Remnants.--Mesonephric remnants occur in the lateral walls of the cervix in up to 22% of women of reproductive and postmenopausal age and they are always an incidental finding.
A pre-tailored panel of antibodies in the study of cervical mesonephric remnants. Gynecol Oncol.
Mesonephric remnants are mesonephric duct vestiges that can be identified histologically in both the male and female genital tract.
Mesonephric remnants of the prostate: incidence and histologic spectrum.
Mesonephric Remnants.--These rare remnants in needle biopsy and TUR material can undergo hyperplasia where there might be a greater chance of being misdiagnosed as prostatic adenocarcinoma.
Florid hyperplasia of mesonephric remnants involving prostate and periprostatic tissue: possible confusion with adenocarcinoma.
may give rise to tumors occurring in the retroperitoneum, gonads, and the inguinal region, whereas the remains of the pronephros may account for those tumors occurring more cranially (mediastinum and the chest wall).