mesoblastic nephroma

mes·o·blas·tic ne·phro·ma

a spindle cell neoplasm of the infant and, rarely, adult kidney with entrapped renal tubules.

mesoblastic nephroma

(1) Congenital mesoblastic nephroma, see there.
(2) Wilms, tumour, see there.
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Two cases each of urothelial carcinoma of the renal pelvis, squamous cell carcinoma and one case of mesoblastic nephroma were the other tumours recorded in the study.
Detection of the ETV6-NTRK3 chimeric RNA of infantile fibrosarcoma/cellular congenital mesoblastic nephroma in paraffin-embedded tissue: application to challenging pediatric renal stromal tumors.
Different types of pediatric renal tumors are known, the commonest of which is Wilms tumor or nephroblastoma, other less common tumors are nephroblastomatosis, rhabdoid malignant tumor, clear cell sarcoma, congenital mesoblastic nephroma and multilocular cystic nephroma3.
Previously, the ETV6-NTRK3 translocation has been described in infantile fibrosarcoma (11), congenital mesoblastic nephroma, and acute myelogenous leukaemia (2, 7, 8).
Congenital mesoblastic nephroma is the most common renal tumor in the newborn, with a mean age of presentation of less than 3 months and an association with polyhydramnios [10].
Congenital mesoblastic nephroma (CMN), the most common congenital renal neoplasm, also shows a biphasic architecture with cysts and tubules embedded in abundant spindle cell stroma and, hence, is morphologically very similar to MEST.
Alon, "Parathyroid-hormone-related protein-mediated hypercalcemia in benign congenital mesoblastic nephroma," Pediatric Nephrology, vol.
Differentials for a cystic-solid abdominal mass with calcifications in neonates and early infancy include mesoblastic nephroma, neuroblastoma, gastrointestinal stromal tumors, lymphangiomas, and teratomas.
It is to be noted that these fusions have also been observed in other neoplasms such as acute myeloid leukemia, congenital mesoblastic nephroma, and fibrosarcoma, [30] suggesting that the fusion protein has transforming activity in cells of different lineages.
The origin of the tumour remains unclear, but some believe it arises from the urothelium.[sup.2] Ossification can be the result of the osteogenic potential of the urothelial cells.[sup.1,2] The ossification and mesenchymal components are similar to mesoblastic nephroma histologically.[sup.5,10] The mass is described as congruent with the renal medulla, in particular the papillae of the renal pyramids.
Cellular mesoblastic nephroma (infantile renal fibrosarcoma): institutional review of the clinical, diagnostic imaging, and pathologic features of a distinctive neoplasm of infancy.
(3,7,8) However, several other non-salivary gland neoplasms harbor this rearrangement, including secretory carcinoma of breast, infantile fibrosarcoma, congenital mesoblastic nephroma, and some cases of acute myeloid leukemia.