In medically refractory epilepsy patients, careful analysis for signs of mesial temporal sclerosis
is undertaken, as it is the most common pathology found in these patients.
Using this technique, mesial temporal sclerosis is diagnosed when there is hippocampal volume loss and increased T2-weighted signal with loss of normal internal hippocampal architecture.
In patients with mesial temporal sclerosis, the intracarotid amobarbital procedure (IAP) is used to evaluate language and memory competence in the contralateral hemisphere prior to temporal lobe surgery.
Mesial Temporal Sclerosis
Vs Other Diagnosis: 17 out of the 39 cases with positive MRI findings (43.6%) showed features of Mesial Temporal Sclerosis
Although, a subgroup of patients with mesial temporal sclerosis on cranial MR images were chosen for comparisons with the rest of the patient population with regard to addictive behavior, this did not reveal any significant results.
Cerebral lesions of epilepsy patients and their locations on cranial magnetic resonance imaging MTS C D H S Tm M Frontal 1 Temporal 16 2 3 5 Occipital 2 Parietal 1 2 Multi lobar 1 1 6 Subcortical 4 Number 16 2 1 4 17 8 6 MTS: mesial temporal sclerosis; C: cavernoma; D: dysplasia; H: heterotopia; S: sequeale lesions; Tm: tumor; M: miscellaneous causes Table 3.
Pathology was cortical dysplasia (36) encephalomatacia (7), tumor (4), mesial temporal sclerosis
(5), and Rasmussen).
Avoiding prolonged focal febrile seizures is a legitimate goal because of their association in prospective MRI studies with development of mesial temporal sclerosis
, the pathologic lesion underlying a lifelong refractory temporal lobe epilepsy