mesial temporal sclerosis


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia.

mesial temporal sclerosis

A condition characterised by induration of the middle temporal lobe, associated with cortical dysplasia and intractable temporal lobe epilepsy.

Aetiology
Major cerebral trauma, infection, febrile illness in childhood; most patients are seizure-free after ablative surgery.

mesial temporal sclerosis

Abbreviation: MTS
Atrophy of neurons and scarring in the temporal lobe of the brain, typically in the hippocampus. It is both a cause and an effect of temporal lobe epilepsy. Some patients with focal seizures and a clearly defined area of MTS have significant improvement in seizure activity when the affected area of the temporal lobe is surgically removed.
See also: sclerosis
References in periodicals archive ?
In medically refractory epilepsy patients, careful analysis for signs of mesial temporal sclerosis is undertaken, as it is the most common pathology found in these patients.
Using this technique, mesial temporal sclerosis is diagnosed when there is hippocampal volume loss and increased T2-weighted signal with loss of normal internal hippocampal architecture.[12]
In patients with mesial temporal sclerosis, the intracarotid amobarbital procedure (IAP) is used to evaluate language and memory competence in the contralateral hemisphere prior to temporal lobe surgery.
Mesial Temporal Sclerosis Vs Other Diagnosis: 17 out of the 39 cases with positive MRI findings (43.6%) showed features of Mesial Temporal Sclerosis.
Although, a subgroup of patients with mesial temporal sclerosis on cranial MR images were chosen for comparisons with the rest of the patient population with regard to addictive behavior, this did not reveal any significant results.
Cerebral lesions of epilepsy patients and their locations on cranial magnetic resonance imaging MTS C D H S Tm M Frontal 1 Temporal 16 2 3 5 Occipital 2 Parietal 1 2 Multi lobar 1 1 6 Subcortical 4 Number 16 2 1 4 17 8 6 MTS: mesial temporal sclerosis; C: cavernoma; D: dysplasia; H: heterotopia; S: sequeale lesions; Tm: tumor; M: miscellaneous causes Table 3.
Pathology was cortical dysplasia (36) encephalomatacia (7), tumor (4), mesial temporal sclerosis (5), and Rasmussen).
Avoiding prolonged focal febrile seizures is a legitimate goal because of their association in prospective MRI studies with development of mesial temporal sclerosis, the pathologic lesion underlying a lifelong refractory temporal lobe epilepsy