C, Periodic Schiff-Methenamine stain showing proliferation of mesangial cell
and mesangial matrix (x400).
In addition, oxidized low-density lipoproteins and triglyceride-rich lipoproteins, which can have increased levels due to the overproduction of very-low-density lipoprotein and the promotion of atherogenic dyslipidemia from the fatty liver, could induce mesangial cell
proliferation and glomerular injury, ultimately resulting in renal injury (32).
A mesangial cell
(black arrow) is stained by desmin.
Diffuse segmental double-contours of the glomerular basement membrane and mesangial cell
hypercellularity were identified in nonsclerotic glomeruli, exhibiting a membranoproliferative glomerulonephritis-like pattern (Figure 1(a)).
Fang, "Screening nephroprotective compounds from cortex Moutan by mesangial cell
extraction and UPLC," Archives of Pharmacal Research, vol.
[2, 3] Hyperglycemia is associated with an increase in mesangial cell
proliferation and hypertrophy, as well as increased matrix production and basement membrane thickening.
Type IV collagen and laminin regulate glomerular mesangial cell
susceptibility to apoptosis via beta(1) integrin-mediated survival signals.
Grade II: slight mesangial cell
proliferation and increased matrix were observed.
Activation of mesangial cell
signaling cascades in response to mechanical strain.
To the Editor: In 2003, two cDNA strands were identified in a human mesangial cell
line during experimental screening for genes upregulated by angiotensin II (1).
Angiotensin II, the main effector of this pathway and a potent vasoconstrictor, causes glomerular hyperfiltration, mesangial cell
proliferation, ROS generation and expansion of ECM, leading to tissue fibrosis.
Primary pulmonary squamous cell carcinoma associated with elevated IL-6, leukocytosis, hypercalcemia, phagocytosis, reactive lymphadenopathy and glomerular mesangial cell
proliferation via the production of PTH-rP and G-CSF.