mesangial cell


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mes·an·gi·al cell

a phagocytic cell in the capillary tuft of the renal glomerulus, interposed between endothelial cells and the basement membrane in the central or stalk region of the tuft.
References in periodicals archive ?
C, Periodic Schiff-Methenamine stain showing proliferation of mesangial cell and mesangial matrix (x400).
In addition, oxidized low-density lipoproteins and triglyceride-rich lipoproteins, which can have increased levels due to the overproduction of very-low-density lipoprotein and the promotion of atherogenic dyslipidemia from the fatty liver, could induce mesangial cell proliferation and glomerular injury, ultimately resulting in renal injury (32).
Diffuse segmental double-contours of the glomerular basement membrane and mesangial cell hypercellularity were identified in nonsclerotic glomeruli, exhibiting a membranoproliferative glomerulonephritis-like pattern (Figure 1(a)).
Fang, "Screening nephroprotective compounds from cortex Moutan by mesangial cell extraction and UPLC," Archives of Pharmacal Research, vol.
[2, 3] Hyperglycemia is associated with an increase in mesangial cell proliferation and hypertrophy, as well as increased matrix production and basement membrane thickening.
Type IV collagen and laminin regulate glomerular mesangial cell susceptibility to apoptosis via beta(1) integrin-mediated survival signals.
Grade II: slight mesangial cell proliferation and increased matrix were observed.
Activation of mesangial cell signaling cascades in response to mechanical strain.
To the Editor: In 2003, two cDNA strands were identified in a human mesangial cell line during experimental screening for genes upregulated by angiotensin II (1).
Angiotensin II, the main effector of this pathway and a potent vasoconstrictor, causes glomerular hyperfiltration, mesangial cell proliferation, ROS generation and expansion of ECM, leading to tissue fibrosis.
Primary pulmonary squamous cell carcinoma associated with elevated IL-6, leukocytosis, hypercalcemia, phagocytosis, reactive lymphadenopathy and glomerular mesangial cell proliferation via the production of PTH-rP and G-CSF.