mercapturic acid


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Related to mercapturic acid: glucuronide, NAPQI

mer·cap·tu·ric ac·id

(mer-kap-tyūr'ik as'id),
A condensation product of l-cysteine with aromatic compounds, such as bromobenzene, and usually acetylated; formed biologically via glutathione in the liver and excreted in the urine; an S-substituted N-acetylated l-cysteine. Compare: mercapturic acid pathway.
Farlex Partner Medical Dictionary © Farlex 2012

mer·cap·tu·ric ac·id

(mĕr-kap'tyūr-ik as'id)
A condensation product of l-cysteine with aromatic compounds, such as bromobenzene; formed in the liver and excreted in the urine.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Knockout of CAR in female mice modified the levels of almost all measured urinary pesticide metabolites (Figure 8B); CAR-/ - females had lower levels of chlorpyrifos, captan (captan SO3) and boscalid metabolites compared to their WT counterparts, and higher levels of boscalid mercapturic acid. [sup.1]H-NMR analysis of plasma samples showed no significant differences in plasma metabolomics between [CAR.sup.-/-] female mice fed control chow and those fed pesticide chow (Figure S8D).
Mercapturic acids as metabolites of alkylating substances in urine samples of German inhabitants.
Biosynthesis of mercapturic acids from allyl alcohol, allyl esters and acrolein.
Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) and W,W-dimethylformamide (AMCC) in human urine using liquid chromatography/tandem mass spectrometry.
The CDC has measured the hemoglobin adducts of acrylamide and its metabolite glycidamide (CDC 2009) and plans to measure urinary mercapturic acid metabolites of acrylamide and glycidamide in NHANES participants (Alwis et al.
At present, the CDC plans to perform benzene biomonitoring in NHANES by measuring urinary mercapturic acid metabolites (Alwis et al.
The CDC plans to measure urinary mercapturic acid metabolites of many volatile organic compounds (VOCs) in NHANES samples, and possibly some of these halogenated VOCs could be integrated into this method (Alwis et al.
To a minor extent, StO is conjugated with glutathione by glutathione S-transferases (GSTs), resulting in subsequent formation of phenyl hydroxyethyl mercapturic acids (PHEMAs), excreted in urine.
Polymorphism of xenobiotic-metabolizing enzymes and excretion of styrene-specific mercapturic acids. Chem Res Toxicol 14:1393-1400.
Urinary excretion of specific mercapturic acids in workers exposed to styrene.