mercaptoethanol agglutination inhibition test
mercaptoethanol agglutination inhibition testA test that differentiates between IgG and IgM as the immunoglobulin responsible for an agglutination reaction.
The MAIT is based on mercaptoethanol’s disrupting the disulfide bonds needed to maintain IgM as a 5-molecule complex; IgM antibody agglutination does not occur after mercaptoethanol treatment, while IgG agglutination remains intact.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.