menopausal syndrome


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men·o·pau·sal syn·drome

recurring symptoms experienced by some women during the climacteric period; they include hot flashes, chills, headache, irritability, and depression.

menopause

The cessation of menstrual activity in women due to failure to form ovarian follicles, which normally occurs at age 45–50; menopause < age of 40 is considered premature.

Clinical findings
Menstrual irregularity, vasomotor instability, hot flushes, irritability, increased weight, painful breasts, dyspareunia, increased/decreased libido, atrophy of urogenital epithelium and skin, ASHD, MI, strokes, and osteoporosis (which can be lessened by hormone replacement therapy (HRT), the disadvantage of which is an increase in endometrial and breast cancer, possibly hypertension, thromboembolism and gallbladder disease).

Physiological changes
• Bladder—Cystourethritis, frequency/urgency, stress incontinence.
• Breasts—Decreased Size, softer consistency, sagging.
• Cardiovascular—Angina, ASHD, CAD.
• Endocrine—Hot flashes/flushes.
• Mucocutaneous—Atrophy, dryness, pruritus, facial hirsutism, dry mouth. 
• Neurologic—Psychological, sleep disturbances.
• Pelvic floor—Uterovaginal prolapse.
• Skeleton—Osteoporosis, fractures, low back pain. 
• Vagina—Bloody discharge, dyspareunia, vaginitis. 
• Vocal cords—Deepened voice.
• Vulva—Atrophy, dystrophy, pruritus.
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References in periodicals archive ?
With an increment in life expectancy the demand for the treatment of menopausal syndrome (MS) has gained importance in India.
A question in the second questionnaire ("Have you seen cases in which nausea was a part of the menopausal syndrome?") asked investigators to consider whether the nausea they observed in older women treated with DES was a symptom of menopause instead of a toxic reaction to DES.
For example, one investigator wrote, "Nausea is often part and parcel of the menopausal syndrome...."(89) The use of the word "syndrome" in reference to menopause signals that this author agrees with the view implied by the question, that menopause is a disease.
As compared with hormone treatment, the different mechanism of action of this plant extract provides a new option for the treatment of patients with menopausal syndrome, who are not suitable or reluctant to accept hormone treatment.
The results showed that Kuntai capsule could alleviate climacteric symptoms effectively in these patients, and had more obvious efficacy on the patients in menopausal transition period, indicating that the treatment effects of Kuntai capsule on menopausal syndrome might be associated with the improvement of ovarian function, bringing the benefit of the absence of E2-like adverse reaction in Kuntai capsule.