Elliotts B Solution (buffered intrathecal electrolyte/dextrose injection) is indicated as a diluent for the intrathecal administration of methotrexate sodium and cytarabine for the prevention or treatment of meningeal leukemia
or lymphocytic lymphoma.
Neurotoxicity and elevated cerebrospinal-fluid methotrexate concentration in meningeal leukemia
. N Engl 3 Med 1973;289:770-3.
Leukemia involvement of the central nervous system most commonly presents as meningeal leukemia
; intracerebral granulocytic sarcoma (IGS) is rare.
Prevention of meningeal leukemia
, review of 20 years of research and current recommendations.