mendelian


Also found in: Dictionary, Thesaurus, Wikipedia.
Related to mendelian: Mendelian population

men·de·li·an

(men-dēl'ē-ăn),
Attributed to or described by Gregor Mendel; usually referring to the behavior and the mechanism of the genetic transmission of single-locus traits.

Mendelian

(mĕn-dē′lē-ən, -dēl′yən)
adj.
Of, relating to, or designating Gregor Mendel or his theories of genetics.

mendelian

adjective
(1) Referring to a type of inheritance in which a specific trait is affected by a set of alleles of a single gene.
(2) Referring to a type of inheritance in which genetic information is transmitted by one or more nuclear genes, as opposed to cytoplasmic or epigenetic mechanisms.
(3) Referring to the principles formulated by Gregor Mendel, the father of modern genetics.

men·de·li·an

(men-dē'lē-ăn)
Attributed to or described by Gregor Mendel; usually referring to the behavior and the mechanism of the genetic transmission of single-locus traits.
References in periodicals archive ?
The choice of approach has depended on the pattern of segregation of disease--whether consistent with Mendelian ratios or polygenic complexity.
Finally, to be sure that physical activity was affecting the risk for depression, and not the other way around, the scientists repeated the Mendelian style of analysis on a separate large genetic database.
An association that is observed using Mendelian randomisation therefore strengthens the inference of a causal relationship.
Thus, we predict the emergence of clinical RNA-seq using target tissue merged with clinical information will tremendously enhance the diagnostic output of Mendelian disorders and enhance knowledge of gene variant--disease associations.
Mendelian disorders are inherited diseases that occur because of the mutation (defect) of a single gene.
Genetic conditions caused by a mutation in a single gene follow predictable patterns known as Mendelian inheritance.
Other articles discuss gene and variant annotation for Mendelian disorders in the era of advanced sequencing technologies; the yin and yang of autism genetics: how rare de novo and common variations affect liability; life as a clinical geneticist; charting the new terrain of precision prevention; participatory genomic research: ethical issues from the bottom up to the top Down; and application of panel-based tests for inherited risk of cancer.
The Mendelian spirit has dominated genetics since the middle of the twentieth century, especially the Human Genome Project and the production of full DNA sequences of many people.
Whereas many of these markers are tested to see if they are within the Hardy--Weinberg equilibrium, very few markers developed for pest species are tested to ensure the selected alleles behave according to the laws of Mendelian inheritance.
In a recent Mendelian randomization analysis, researchers identified a causal association of high circulating BCAAs with T2D risk and proved the causal role of BCAA metabolism in the T2D etiology [9].
The segregation models can be classified according to the number of baseline parameters for susceptibility in the model: one susceptibility type (no segregation, [[beta].sub.AA] = [[beta].sub.AB] = [[beta].sub.BB]), two susceptibility types (dominant or recessive Mendelian transmission, [[beta].sub.AA] = [[beta].sub.AB], or [[beta].sub.AB] = [[beta].sub.BB]), and three susceptibility types ([[beta].sub.AA], [[beta].sub.AB], [[beta].sub.BB]) need to be estimated individually.
Higher levels of LDL cholesterol, HDL cholesterol, and triglycerides over a lifetime are protective against type 2 diabetes, a Mendelian randomization study has shown.