melanotic schwannoma

melanotic schwannoma

A rare form of schwannoma characterised by heavy deposition of melanin pigment (Fontana-Masson, S-100, HMB-45, all +ve) linked to melanosomes and premelanosomes. It is often (50% of cases) associated with Carney syndrome (myxomas in various sites, spotty pigmentation, endocrine hyperactivity).

Prognosis
Most melanotic schwannomas behave benignly; they may metastasise.
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References in periodicals archive ?
The article by Alexiev et al highlights the importance of diagnostic recognition, ancillary molecular genetic testing, and close clinical follow-up of patients with melanotic schwannoma. Deeken-Draisey et al review current procedural terminology (CPT) coding for surgical pathology, highlighting that the appropriate extent of physician involvement in CPT coding is a matter of some debate, and a multidisciplinary approach involving both health care providers and professional coders appears to be the best way to achieve accuracy.
Current Issues in Surgical, Hematologic, and Cytologic Pathology
Psammomatous melanotic schwannoma, plexiform schwannoma, microcystic/reticular schwannoma are further variants of schwannoma8,9.
Psammomatous melanotic schwannoma. A distinctive, heritable tumor with special associations, including cardiac myxoma and the Cushing syndrome.
GASTRIC SCHWANNOMA - A CASE REPORT
Soon, "Solitary gastric melanotic schwannoma: sonographic findings," Journal of Clinical Ultrasound, vol.
Gastric Schwannoma: A Tumor Must Be Included in Differential Diagnoses of Gastric Submucosal Tumors
Melanotic Schwannoma (MS) is a rare, distinctive, potentially malignant neoplasm that is categorized as a variant of Schwannoma [1,2].
Melanotic Schwannoma can be divided into psammomatous and nonpsammomatous types and about half of the cases with psammomatous MS are related to Carney complex [1].
Melanotic Schwannomas Are Rarely Seen Pigmented Tumors with Unpredictable Prognosis and Challenging Diagnosis
Pathological types of tumors included schwannoma (31 cases) [Figure 5], epidermoid cyst (12 cases), neurofibroma (5 cases), hemangioma (2 cases), and melanotic schwannoma (1 case).
Three-dimensional Fluoroscopy-based Navigation for the Pedicle Screw Placement in Patients with Primary Invasive Spinal Tumors
The differential diagnoses include pigmented (melanotic) neurofibroma, psammomatous melanotic schwannoma, and desmoplastic (neurotrophic) melanoma.
Bednar tumour: an infrequent diagnosis
They acquire melanin and these lesions include Meningioma, Medulloblastoma, Astrocytoma, Melanotic Schwannoma, Pitutary tumours and Choroid plexus Papilloma.
Primary CNS melanoma in an albino: a rare case report
Intramedullary melanotic schwannoma. Report of a case and review of the literature.
Ventriculostomy for treatment of persistent cervical cerebral spinal fluid leak after excision of cervical schwannoma: a case study
Melanotic schwannoma (MS) is a nerve sheath tumor with a uniform composition of variably melaninproducing Schwann cells and metastatic potential.
Pathology of Melanotic Schwannoma
Psammomatous melanotic schwannoma may present rarely as a colorectal polyp comprising epithelioid cells with psammoma bodies and melanin pigment.
Neurogenic Polyps of the Gastrointestinal Tract: A Clinicopathologic Review With Emphasis on Differential Diagnosis and Syndromic Associations

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